摘要
目的提高原发性十二指肠癌的诊断水平。方法选择46例原发性十二指肠癌患者，其中男性26例．女性20例：年龄31-71岁，平均年龄62_3岁。行内镜诊断和病理活组织检查或术后病理组织检查。回顾性分析其临床、内镜及病理学关系。结果46例十二指肠癌发生于十二指肠球部9例，水平部5例．乳头部30例．乳头下段2例。病理活组织检查或术后病理学诊断示中分化腺癌8例，低分化腺癌26例．印戒细胞癌10例．未分型2例。结论临床应提高对原发性十二指肠癌的警惕性；原发性十二指肠癌以十二指肠乳头部好发，病理分型以腺癌为主，诊断首选上消化道内镜及活组织检查，内镜操作时应尽可能观察到十二指肠降部以下，特别应注意观察乳头部。对十二指肠球部溃疡反复治疗效果不佳者，应提高警惕，及时进行活组织检查。手术切除尤其是胰十二指肠切除术是最常用、最可靠的治疗方法。
Objective To improve the diagnosis level of primary duodenum cancer. Methods A total of 46 cases with primary duodenum cancer were enrolled, included 26 males and 20 females, who were aged 31 - 71 years old with a mean age of 62.3. The clinical data, digestive endoscope exam, surgery treatment and pathological data were retrospectively analyzed. Results In 46 cases, 9 cases occurred in duodenal bulb, 5 cases in pars horizontals duodenal, 30 cases in duodenal papilla and 2 cases at inferior segment of duodenal papilla. The postoperative pathological data showed that moderately differentiated adenocaroinoma in 8 cases, 26 cases of poorly differentiated adenocarcinoma, 10 cases of signet-ring cell carcinoma, and 2 cases of undifferentiated adenocarcinoma. Conclusion It is demonstrated that the clinical should alert the development of primary duodenum cancer. The primary duodenum cancer occurs in duodenal papilla, most of pathology group is adenoearcinoma. The preferred diagnosis method is digestive endoscope and biopsy. The endoscopic operation and observation should be focused on the descending duodenum, especially the duodenal papilla. For duodenal ulcer patients who do not have good treatment effect by repeatedly therapy, biopsy should be performed timely. The most reliable treatment to primary duodenum cancer is surgery especially for pancreaticoduodenectomy duodenal.
出处
《生物医学工程与临床》
CAS
2014年第1期56-59,共4页
Biomedical Engineering and Clinical Medicine
