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高血压早期肾损伤的筛查及相关因素分析 被引量:4

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摘要 目的了解内蒙古自治区巴彦淖尔地区随机高血压人群中早期肾损伤的发病情况及相关因素。方法对976例高血压患者进行问卷调查基本情况,计算体质量指数(BMI);应用免疫比浊法检测尿微量白蛋白,碱性苦味酸法检测尿肌酐,尿白蛋白与肌酐比值(ACR)≥30mg/g时为阳性;同时空腹12h以上检测血肌酐、尿酸、总胆固醇(TC)、三酰甘油(TG)等。结果976例高血压患者中,ACR阳性184例,占18.9%(184/976)。ACR阳性患者BMI、收缩压及血尿酸明显高于ACR阴性患者[(26.8±3.1)kg/m2比(24.1±3.0)kg/m2、(175±25)mmHg(1mmHg=0.133kPa)比(162±20)mmHg、(397.7±51.3)肛mol/L比(291.4±52.1)μmol/L],差异有统计学意义(P〈0.05);而性别构成、年龄、吸烟史、高血压家族史、降压药物治疗史、高血压病程、舒张压、TC、TG、血肌酐比较差异无统计学意义(P〉0.05)。结论内蒙古自治区巴彦淖尔地区随机高血压患者早期肾损伤发生率较高,相关危险因素包括收缩压、BMI及血尿酸。
出处 《中国医师进修杂志》 2014年第1期36-37,共2页 Chinese Journal of Postgraduates of Medicine
基金 基金项目:内蒙古自治区卫生厅科研课题(2010289)
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