摘要
目的研究尺胫针疗法的镇痛机理,为临床应用提供实验依据。方法将小鼠分为模型组、腕踝针组及尺胫针组,于小鼠第二、三跖趾关节之间皮下注射5%甲醛溶液致痛造模,观察各组不同时间点小鼠血清5-HT含量变化。结果血清5-HT含量在造模后4 h即明显升高;于一、二次治疗后,尺胫针组和腕踝针组均低于模型组(P<0.01;P<0.05),而尺胫针组较腕踝针组更低(P<0.05)。结论尺胫针与腕踝针疗均可降低足底注射甲醛溶液致痛小鼠模型血清5-HT含量,尺胫针组降低作用优于腕踝针组。
Abstract ： Objective to study the analgesic mechanism of ruler and needle therapy, to provide the experimental basis for clinical application. Methods the mice were divided into model group, wrist ankle acupuncture group and the acupuncture group scale, between the second and third mice metatarsophalangeal joint pain induced by subcutaneous injection of 5 % formaldehyde solution model, the changes of serum 5 - HT levels at different time points were observed in mice. Results the content of 5 - HT in serum after 4H is significantly increased; in one or two after the first treatment, ruler and needle group and the wrist ankle acupuncture group were lower than those in the model group （ P 〈 0.01 ; P 〈 0.05 ）, and the ruler and needle group than the wrist ankle acupuncture group was lower （ P 〈 0.05 ）. Conclusion ulnar wrist ankle acupuncture needle and tibial plantar injection can reduce the content of 5 -HT in serum formaldehyde solution induced pain model in mice, foot and needle group decreased function is better than that of wrist ankle acupuncture group.
出处
《陕西中医学院学报》
2014年第1期67-68,80,共3页
Journal of Shaanxi College of Traditional Chinese Medicine
基金
陕西省教育厅课题(12JK0700)
陕西省中医管理局课题(le10)
咸阳市科技局课题[2011K13-03(7)]
