摘要
目的 :观测中药方剂进入机体后的“时间 效应”关系。方法 :将右归丸灌服于家兔体内 ,监测其血中 2 4h微量元素的代谢情况。结果 :发现右归丸被吸收利用后 ,形成一个“微量元素特征谱” ,其浓度存在着“时间 效应”关系 ,多数元素的“血药浓度”峰值出现在 3h左右。结论 :“微量元素特征谱”可以作为药物的“生物药效探针” ,对中药的药效给予客观评价。
OBJECTIVE:To provide a diagnostic index for supervision conistency in blood of Chinese traditional medicine and prescription;to study the relation of time effect after the herbs and prescriptions enter into body.METHODS:After You Gui Wan was absorbed,a diagnostic table of trace elements were formed,and there is a dependent relation of time effect.RESULTS:The peak value of drug consistency of trace elements in blood is formed after pouring You Gui Wan hours.CONCLUSIONS:The diagnostic table of trace element can be a good probe for biologic pharmacodynamics.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2001年第1期22-25,共4页
Chinese Journal of Hospital Pharmacy
关键词
右归丸
药效学
微量元素
血药浓度
中药
You Gui Wan
pharmacodynamics
trace element
blood drag consistency
