摘要
目的:探讨西格列汀联合甘精胰岛素治疗糖尿病的效果。方法:收治糖尿病患者58例,将入组的所有患者采用随机的方式进行分组,一组为观察组共30例患者,本组服用西格列汀联合甘精胰岛素进行治疗;一组为对照组共28例患者,本组服用阿卡波糖联合甘精胰岛素进行治疗。将两组疗效进行比较,观察两组治疗后FBG、2hPG、HbA1C、低血糖发生率。结果:两组治疗后,FBG、2hPG、HbA1C指标均较前下降(P<0.01)。且观察组低血糖发生率低于对照组(P<0.05)。结论:西格列汀联合甘精胰岛素能有效控制血糖,低血糖发生率低,具有安全方便的特点。
Abstract Objective：We investigate the therapeutic effect of sitagliptin combomed with insulin glargine in treatment of diabetes mellitus.Methods＇：We have treated 58 cases of diabetic patients between 2010 November to 2013 March,these patients were randomly divided into two groups. The observation group itleiuded 30 patients and these pa-tients were treated by sitagliptin combined with insulin glargine.The control group in-cluded 28 patients and these patients were treated by Acarbose combined with in,ulin glargine.Finally,results of treatment of two groups such as FBG,2hPG,HbAic,incidence of hypoglycemia were compared.Results：Af-ter tteafment,FBG,2hPG,HbAic index of the two groups were decreased （P〈0.01）.The incidence of hypoglycemia of observation group was lower than the control group（P 〈 0.05）.Conelusion： Sitagliptin combined with insulin glargine can effectively control blood glueose with Low rates of hypoglycemia and of is safe and convenient.
