摘要
目的探讨不同氧分压环境下(20%O2&5%O2)体外受精-胚胎移植中胚胎发育潜能与临床结局关系。方法选择2012年9月至2012年11月年在郑大三附院生殖医学中心行助孕治疗的280个周期,分别为IVF(n=200),ICSI(n=80)。随机分组:研究组(5%氧分压)和对照组(20%氧分压),对比两组间正常受精率、卵裂率、优质胚胎率、生化妊娠率、临床妊娠率和着床率。结果实验组与对照组正常受精率、卵裂率、优质胚胎率、生化妊娠率、临床妊娠率和着床率无统计学差异。结论人类早期胚胎在低氧环境下进行体外培养是有利的,可以获得更好结局。
Objective ： Discuss of different oxygen partial pressure environments （20% 02 ＆5% 02 ） for in vitro fertilization em-bryo transfer embryo developmental potential and clinical outcomes. Methods： 280 cycles with selection in three affiliated hospital hu-man reproductive center from 2012 March to 2012 May of progesterone treatment, respectively IVF （ n = 200）, ICSI （ n = 80）. Divided into study group （5% oxygen） and control group （20% oxygen）. Comparison of the two groups of normal fertilization rate, cleavage rate, good quality embryo rates, biochemical pregnancy rate, clinical pregnancy rate and implantation rate. Results ： There was no sig-nificance comparing respectively the two groups of normal fertilization rate, cleavage rate, good quality embryo rates, biochemical preg-nancy rate, clinical pregnancy rate and implantation rate. Conclusions： In early human embryos in hypoxia envionment were cultured is favorable, Can get a better outcome.
出处
《中国优生与遗传杂志》
2014年第1期93-94,共2页
Chinese Journal of Birth Health & Heredity
关键词
氧分压
体外受精-胚胎移植
妊娠
Partial pressure of oxygen
In vitro fertilization embryo transfer
Pregnancy
