摘要
目的 :为提高颅内肿瘤手术麻醉的安全。方法 :随机选择颅内肿瘤择期手术病人 16 0例。全部病人均采用快速诱导气管内插管静脉复合麻醉。于围麻醉期采用了降低颅内压 (ICP)、改善脑灌注压 (CPP)、减少有害的应激反应等措施 ,并对比观察了麻醉期间平均动脉压 (MAP)、心率 (HR)及 ICP、CPP的变化。结果 :麻醉平稳、术终病人苏醒迅速 ,不同麻醉期间 MAP、HR与麻醉前比无明显差异 P>0 .0 5。 ICP与麻醉前比明显降低 ,P<0 .0 1;CPP比麻醉前水平明显升高且差异显著 ,P<0 .0 1。结论 :颅内肿瘤手术麻醉处理的关键是降低 ICP,维持正常的 CPP(9.3～ 10 .2 7k Pa,70～ 77mm Hg) 。
Objective To study anesthetic safety for the patient with intracranial tumor during the operation.Method 160 patients were randomly selected,which were anesthetized by using the combined anesthesia of tacho-induction endotracheal intubation and vein.Measurements which reduce the intracranial pressure (ICP),improve the cerebral perfusion pressure(CPP)and descrease the harmful stress reaction were adopted in perianesthesia period.The variation of mean arterial blood (MAP),heart rate(HR),ICP and CCP were also compared and observed during the anesthesia.Results The patients in this group are in good state during the anesthesia and regain consciousness rapidly after anesthesia.The MAP and HR in different anesthesia period have no significant difference with those before anesthesia(P>0.01).However,ICP was lower and CPP was higher during anesthesia than before anesthesia(P<0 01).Conclusion The key piont of the anesthesia treatment to the patient during the intracranial tumor operation is to lower the ICP,to maintain normal CPP (9 3～10 27kPa,70～77mmHg)and constant cerebral blood circulation.
出处
《吉林医学》
CAS
2000年第6期326-328,共3页
Jilin Medical Journal
基金
吉林省科委科研基金资助项目!(1998110 7)
关键词
颅内肿瘤
麻醉处理
应激反应
外科手术
Intracranial tumor Operation Anesthesia and Treatment Stress reaction
