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曲美他嗪联合阿托伐他汀钙治疗缺血性心肌病心力衰竭的疗效观察 被引量:23

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摘要 目的探讨曲美他嗪联合阿托伐他汀钙治疗缺血性心肌病心力衰竭的效果。方法将本院2012年2月—2013年2月收治的83例缺血性心肌病心力衰竭患者随机分为对照组(41例)和观察组(42例),两组均给予包括曲美他嗪在内的常规治疗,仅观察组在此基础上加用阿托伐他汀钙治疗;分析两组的临床疗效,治疗前、治疗3个月后的心脏超声指标〔左室射血分数(LVEF)、舒张末期内径(LVEDD)、室收缩末期内径(LVESD)及心排出量(CO)〕并记录治疗期间的不良反应。结果观察组的治疗总有效率(95.24%)高于对照组(80.48%),差异有统计学意义(P<0.05);观察组治疗后LVEF、CO高于对照组,LVEDD、LVESD低于对照组,差异有统计学意义(P<0.05);两组治疗期间的不良反应发生率均较低且差异无统计学意义(P>0.05)。结论曲美他嗪联合阿托伐他汀钙治疗缺血性心肌病心力衰竭的效果较好,可在该类心力衰竭治疗中进行推广。
作者 郭志强
出处 《临床合理用药杂志》 2014年第3期53-54,共2页 Chinese Journal of Clinical Rational Drug Use
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  • 1Go A S,Lee W Y,Yang J,et al.Statin therapy and risks for death and hopitalization in chronic heart filure[J].JAMA,2006,296(17):2105-2111.
  • 2Goldherger J J,Subacius H,Schaechter A,et al.Effects of statin therapy on arrhythmic events and survival in patients with nonischemic dilated cardiomyopathy[J].J Am Coil Cardiol,2006,48(6):1228-1233.
  • 3Stanek B,Frey B,Hulsmann M,el al.Prognostic evaluation of neurohumoral plasma levels befire and during beta-blocker therapy in advanced left ventricular dysfunction[J].J Am Coil Cardiol,2001,38 (2):436-442.
  • 4Kawai K,Hata K,Takaota H,et al.Plasma brain natriuretic peptide as a novel therapeutic indicator in idiopathic dilated cardiomyopathy during Beta-blocker therapy:a potential of hormone guided treatment[J].Am Heart J,2001,141 (6):925-932.
  • 5Dao Q,Krshaswamy P,Kazanergra R,et al.Utility of B-type natriuretic peptide in the diagnosis of congestive heart failure in an urgent-care setting[J].J Am Cardiol,2001,37(2):379-385.
  • 6Cheung B M,Kumana C R.Natriuretic peptides relevance in cardiovascular disease[J].JAMA,1998,280(23):1983-1984.
  • 7Tsutamoto T,Wada A,Maeda K,el al.Plasma brain natriuretic peptide levels as a biochemical marker.of morbidity and mortality in patients with asymptomatic or minimally symptomatic left ventricular dysfunction[J].Eur Heart J,1999,20(24):1799-1807.
  • 8Mnzaffarian D,Minami E,Letterer R A,et al.The effect of atnrvastatin (10mg) on systemic inflammation in heart failure[J].Am J Cardiol,2005,96(12):1699-1704.
  • 9Sola S,Mir M Q,Lerakis S,et al.Atorvastatin improves left ventricular systolic function and serum markers of inflammation in nonischemic heart failure[J].J Am Coil Cardiol,2006,47(2):332-337.
  • 10Yin WH, Chen JW, Jen HL, et al. Independent prognostic value of elevated high-sensitivity C-reactive protein in chronic heart failure[J]. Am Heart J,2004,147(5) :931 -938.

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