摘要
目的:探讨脂蛋白脂酶(LPL)基因T-93G多态性与脑梗死发病的关联性。方法:100例体检健康成人为对照组,100例脑梗死患者为病例组,采用聚合酶链反应-限制性片段长度多态性(PCR-RFLP)方法,检测LPL基因的多态性。结果:病例组及对照组均为-93T,未见突变基因。结论:LPLT-93G基因多态性与脑梗死无关。
Objective：To investigate association between lipoprotein lipase（LPL）gene（T-93G）polymorphism and cerebral ischemia infarction （IC）. Methods： 100 healthy adults were selected as control group,and 100 patients with IC were as case group. LPL T-93G gene polymorphism were detected by polymerase chain reaction- restriction fragment length poly- morphism in two groups. Results：-93Tgenotype were the only genotype of IC patients and control subjects. No mutation gene were observed in two groups. Conclusion ： The LPL T-93G gene polymorphism is not associated with IC.
出处
《山西中医学院学报》
2013年第5期64-65,67,共3页
Journal of Shanxi College of Traditional Chinese Medicine
关键词
脑梗死
脂蛋白脂酶
基因多态性
cerebral ischemia infarction
LPL
gene polymorphism
