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大鼠背部单一穿支蒂皮瓣的实验研究 被引量:13

A perforator-based dorsal flap' s experimental research in the rat He
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摘要 【摘要】目的建立不同单一穿支血管蒂皮瓣的动物模型,探讨单一穿支血管所能营养的最大的皮肤范围。方法选择36只雄雌不限的SD大鼠,分成A、B、C3组,每组12只,以大鼠背部双侧肩胛骨顶点连线为上界、双侧髂棘连线下1em处为下界,分别以旋髂深动脉穿支(DCIA)、后肋间动脉穿支(PIA)及侧胸动脉穿支(LTA)为蒂,设计13cm×6cm皮瓣,术后72h体内注射荧光素钠观察皮瓣染色情况,术后7d观察记录皮瓣成活情况,氧化铅明胶造影显示皮瓣血管结构。结果C组及A组皮瓣远端无荧光染色,B组整个皮瓣出现荧光;C、A、B各组皮瓣的成活率依次增高,组间差异有统计学意义(P〈0.01);A组氧化铅明胶造影显示皮瓣头端坏死区域LTA血管结构部分消失,B组显示各供区血管结构清晰,C组显示尾端坏死区域DCIA血管结构部分消失及紊乱。结论以单一穿支血管蒂为中心可放射性地完整带动其周围多个第2血管供区,第3血管供区远端坏死,在一个方向上血供能到达的最远距离是第3血管供区的穿支入皮点,这对临床上设计穿支皮瓣具有一定理论指导作用。 Objective To develop a new experimental animal model of different a single perforating vessel as its pedicle, and to investigate this vessel can captures how many adjacent angiosomes in different directions. Methods Thirty-six Sprague-Dawly rats of both sexes were used. The rats were divided into group A, group B and group C. Group A: the unilateral deep circumflex iliac perforator artery-
出处 《中华整形外科杂志》 CAS CSCD 北大核心 2014年第1期40-44,共5页 Chinese Journal of Plastic Surgery
基金 国家自然科学基金(81171695) 温州市科技计划项目(Y20080082)
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参考文献11

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共引文献195

同被引文献91

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