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手术联合复方倍他米松注射治疗耳廓瘢痕疙瘩 被引量:13

Treatment of auricular keloids with surgery and intralesional injection of compound Betamethasone
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摘要 【摘要】目的探讨手术去核处理联合定期注射复方倍他米松(得宝松)治疗耳廓瘢痕疙瘩的临床效果。方法2008年1月至2012年1月,治疗186例耳廓瘢痕疙瘩患者,前期根据瘢痕疙瘩大小及患者意愿进行单纯手术(22例)或者单纯注射得宝松(34例)治疗,后期开始进行手术去核处理后定期注射得宝松治疗(130例),所有疗程结束后回访1年,观察并评价3种治疗方法的疗效,将各组数据使用SPSS16.0软件作统计学处理和分析,并使用GraphPad检验方法进行检验。结果单纯手术治疗患者术后有效率仅为54.55%(12/22);单纯得宝松注射组患者瘢痕疙瘩在治疗范围期间皆有所减小,各项临床症状都有所减轻,但停药后,逆转现象明显,有效率为55.88%(19/34);手术去核处理后定期注射得宝松组患者治愈率高,复发病例仅为4例,有效率可高达96.92%(126/130),效果明显优于单纯手术或单纯得宝松注射(P〈0.01)。结论手术去核处理联合得宝松注射可以较好地治疗耳廓瘢痕疙瘩。 Objective To investigate the treatment of auricular keloid with denuclear surgery and intralesional injection of compound Betamethasone. Methods From Jan. 2008 to Jan. 2012, a total of 186 cases of ear keloid were treated by surgery only (22 cases), or intralesional injection of compound Betamethasone(34 cases), or combined denuclear surgry with compound Betamethasone (130 cases). All the patients were followed up for one year. SPSS 16.0 software was used for statistical processing and analysis, and GraphPad inspection method for inspection. Results The effective rate was 54.55% ( 12/ 22)in surgery group and 55.88% (19/34)in injection group. The recurrence was obvious in injection group during the follow-up period. The effective rate was as high as 96. 92% (126/130) in combined ~rouo
出处 《中华整形外科杂志》 CAS CSCD 北大核心 2014年第1期7-10,共4页 Chinese Journal of Plastic Surgery
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