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一种新型疫苗递送系统DepoVax^(TM)的研究进展 被引量：1

Progress in research on DepoVax^(TM),a novel vaccine delivery system
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摘要 DepoVaxTM是一种新型疫苗递送系统,可以作为佐剂,与不同抗原作用,制备多种疫苗,用于肿瘤治疗及多种传染性疾病的预防。DepoVaxTM已被证明能够产生独特的贮存效应,且可吸引抗原提呈细胞至注射位点,从而刺激机体产生更为快速强大的免疫反应。本文就DepoVaxTM的结构和成分、作用机制及应用作一综述。 DepoVaxTM is a novel vaccine delivery system which may be used as an adjuvant. A variety of antigens are formulated with DepoVaxTM to form vaccines which are used for the treatment of cancer and the prevention of various infectious diseases. DepoVaxTM has been proved to create a unique depot effect and attracts antigen-presenting cells to the injection site, thus induces a more rapid and strong immune response. In this paper, the structure, composition, mechanism and application of DepoVaxTM are reviewed.
作者 张洪兵 井申荣
机构地区 昆明理工大学生命科学与技术学院
出处 《中国生物制品学杂志》 CAS CSCD 2014年第1期141-144,共4页 Chinese Journal of Biologicals
关键词 DepoVaxTM 佐剂 疫苗 递送系统 DepoVaxTM Adjuvant Vaccine Delivery system
分类号 R392.33 [医药卫生—免疫学]
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中国生物制品学杂志
2014年 第1期

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