摘要
目的探讨细针穿刺细胞学(fine needle aspirtion cytology,FNAC)在乳腺肿块良、恶性诊断中的价值。方法对1 086例乳腺肿块行FNAC涂片,镜下观察细胞形态,评估肿块性质,其中221例获得术后组织病理学对照。结果 221例乳腺肿块的FNAC与组织病理学诊断对照分析,诊断符合率为96.83%,对恶性肿瘤诊断的敏感性为86.36%,对良性病变诊断的特异性为99.44%,假阴性率(漏诊率)为13.64%,假阳性率(误诊率)为0,潜在假阳性率为0.56%;阳性预测值为97.44%,阴性预测值为96.70%。结论乳腺肿物FNAC检测可准确反映乳腺病变情况,也存在一定的局限性,需要结合组织病理学诊断,提高乳腺肿块良、恶性诊断的准确率。
Purpose To investigate the clinical value of fine needle aspiration cytology （FNAC） on breast masses. Methods A total of 1 086 FNAC cases of breast masses were performed and 221 cases of which were checked with their histopathologic diagnosis. Re- sults A comparison analysis had been made between the fine needle aspiration cytologic diagnosis and the histopathologic diagnosis. The diagnose accordance rate was 96. 83%. The sensitivity of diagnosis of malignant tumor and the specificity of diagnosis of benign le- sion were 86. 36% and 99.44% respectively. The false negative rate, false positive rate and potential false positive rate were 13.64% , 0 and 0.56% respectively. The positive predictive value and negative predictive value were 97.44% and 96. 70% respec- tively. Conclusions FNAC of breast masses can accurately reflect breast lesions, but it has certain limitations. It can improve the di- agnosis of pathological changes in breast masses when combined with histopathology.
出处
《临床与实验病理学杂志》
CAS
CSCD
北大核心
2014年第1期19-22,共4页
Chinese Journal of Clinical and Experimental Pathology
基金
广东省人口和计划生育委员会科研基金(20132039)
关键词
乳腺肿瘤
细针穿刺
细胞学
活组织检查
breast neoplasm
fine needle aspiration
cytology
biopsy tissue
