摘要
对脑动静脉畸形(AVM)立体定向放射外科(SRS)治疗进行随访分析,观察其确切疗效。方法:自1995年5月至1999年10月,采用SRS技术治疗颅内AVM 29例。病灶的靶体积边缘剂量为16～24Gy,平均18.7Gy。对于体积较大的病灶采用体积分次的方法进行治疗。本组病例全部得到随访,随访时间为6～40个月,中位随访时间为17.8个月。结果:11例病人术后复查数字减影血管造影(DSA),其中完全闭塞4例(36.4%),部分闭塞5例(45.5%),2例无变化(18.2%)。另外18例术后复查磁共振(MR),13例(72.2%)于12个月显示AVM体积缩小,5例(27.8%)无变化。结论:SRS是治疗AVM的有效治疗方法,并且应用“全面覆盖,集中照射”和“体积分次”的方法可以更为有效地降低放射并发症。
To analyze therapeutic results of cerebral arteriovenous malformation (AVM) using stereotactic radiosurgery (SRS). Methods:During May 1995 to October 1999,29 patients with AVM were treated with SRS. The surface doses on targets were 16~24 Gy (mean:18.7 Gy).The volume-fraction method was used for a big volume target. All the patients were followed-up 6 to 40 months (mean: 17.8 months). Results:Eleven patients were examined with DSA after operation, among whom 4 cases (36.4%) showed complete obliterations,5 cases (45.5%) showed partial obliterations and 2 cases (18.2% ) showed no change. Other 18 patients were examined with MR,among whom 13 cases (72.2% ) showed significant decreases in AVM volume,and 5 cases (27.8%) showed no change.Conclusion:SRS is an effective method of treating AVM. 'Focusing radiation,treating all over and volume fraction' may decrease the damage of radiation.
出处
《天津医药》
CAS
北大核心
2001年第1期23-25,共3页
Tianjin Medical Journal
关键词
脑动静脉畸形
立体定位技术
放射外科手术
cerebral arteriovenous malformations stereotaxic techniques radiosurgery
