摘要
目的:探讨肾脏小肿瘤(SRMs)(≤4cm)最大径(Dmax)与肿瘤性质之间的相关性。方法:回顾性分析协和医院近3年收治78例SRMs患者的临床资料,将肿瘤Dmax与术后病理结果对照分析。结果:78例SRMs患者中恶性肿瘤61例(78.21%),其中肾透明细胞癌59例(96.72%),肾乳头状腺癌1例(1.64%),肾嫌色细胞癌1例(1.64%);良性肿瘤17例(21.79%),均为肾错构瘤。Dmax<2cm者4例,良性肿瘤2例(50%),恶性肿瘤2例(50%),均为低分级;2cm≤Dmax<3cm者38例,良性肿瘤11例(28.95%),恶性肿瘤27例(71.05%),其中低分级25例(92.59%),高分级2例(7.41%);3cm≤Dmax≤4cm者36例,良性肿瘤4例(11.11%),恶性肿瘤32例(88.89%),其中低分级28例(87.5%),高分级4例(12.5%)。3组之间良性、恶性肿瘤发生率比较差异均有统计学意义(P=0.000),恶性肿瘤核分级中低分级比较差异有统计学意义(P=0.000),高分级比较差异无统计学意义(P=0.067)。结论:随着肾脏小肿瘤Dmax的增加,肿瘤恶性的可能性增加,且核分级多为低分级。
Objective： To explore the correlation between tumor maximum diameter （Dmax） and tumor nature in small renal masses （SRMs）. Method： The clinical data of 78 patients with SRMs in recent three years were retro- spectively analyzed. We performed a contrast analysis between Dmax and postoperative pathologic results. Result： There were 61 （78.21%） malignant tumors including renal clear cell carcinoma 59 cases （96.72 %）, renal papilla- ry adenoearcinoma one case （1.64%） and renal chromophobe cell carcinoma one case （1.64%）. The rest 17 cases （21.79%） were diagnosed of benign tumors. Those were all renal hamartoma. There were two （50%） benign tumors and two （50%） malignant tumors in Dmax〈2 cm group （a total of 4 cases）, which the malignant tumors were low grade. There were 11 （28.95%） benign tumors and 27 （71.05%） malignant tumors in 2 cm≤Dmax〈3 cm group （a total of 38 cases）, which low grade was found in 25 cases （92.59%） and high grade was found in two eases （7.41%）. There were four （11.11%） benign tumors and 32 （88.89%） malignant tumors in 3 cm≤Dmx≤4 em group （a total of 36 cases）, which low grade was found in 28 cases （87.5%） and high grade was found in four cases （12.5 %）. Differences of incidence of benign tumors and malignant tumors were statistically significant （P=0. 000）. Differences of incidence of low grade malignant tumors among the above three groups were statisti- cally significant （P= 0. 000）, but no significant differences was found in incidence of high grade malignant tumors （P=0. 067）. Conclusion： With the increase of the maximum diameter of SRMs, the risk of malignant tumor will become higher, which the nuclear grade is mainly low grade in malignant SRMs.
出处
《临床泌尿外科杂志》
2014年第1期45-47,共3页
Journal of Clinical Urology
关键词
肾脏小肿瘤
最大径
肿瘤性质
相关性
small renal masses
maximum diameter
tumor nature
correlation
