摘要
目的探讨老年COPD(慢性阻塞性肺病)患者的肺功能和血清甲状腺激素的关系。方法随机选取75例COPD患者和25例健康对照者。分别对其进行肺功能、TSH水平及血清FT3、FT4、TT3、TT4的测定。另选24例Ⅳ级COPD老年患者,并将其分为存活组和死亡组两组,对两组患者的血清甲状腺激素水平进行比较,并对其肺功能和甲状腺激素的关系进行分析。结果Ⅲ级和Ⅳ级老年COPD患者的FT3和TT3值都比对照组要低(P<0.01),所选出的24例Ⅳ级老年COPD病人中,死亡组的TT4、FT3和TT3值都比存活组要低(P<0.05),两组的TSH差异无统计学意义(P>0.05)。结论随着病情的加重,老年COPD病人的血清甲状腺激素会出现异常,患者肺功能与其甲状腺激素水平存在很大相关性,对血清甲状腺激素的检测对COPD病情的诊断非常有利。
Objective To discuss the relationship between pulmonary function of elderly patients with COPD （chronic obstructive pulmonary disease） and serum thyroid hormone. Methods 75 COPD patients and 25 healthy controls were randomly selected. Pul- monary function, TSH level, serum FT3, FT4, TT3 and TT4 were measured in them. And other 24 elderly patients with grade IV COPD were selected and divided into survival group and death group. Serum thyroid hormone level was compared between the two groups, and the relationship between pulmonary function and thyroid hormone was analyzed. Results The FT3 value and Tl＇3 value of elderly patients with grade ⅢCOPD or grade IVCOPD are lower than those of the control group （P〈0.01）. Of the selected 24 elderly patients with grade IV COPD, TF4 value, FT3 value, and rlT3 value of the death group are lower than those of the survival group（P〈0.05）, but the difference in TSH value between the two groups is not statistically significant（P〉0.05）. Conclusion As the illness is aggravating, the serum thyroid hormone of senile COPD patients can become abnormal; the lung function of the patients is strongly correlated with the level of thyroid hormone. Therefore, the detection of serum thyroid hormone is beneficial to the diagnosis of COPD disease.
出处
《中外医疗》
2013年第33期24-25,共2页
China & Foreign Medical Treatment
