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细胞色素P450酶在药物代谢及开发研究中的应用 被引量:12

CYP450 and Its Application in the Study on New Drug Metabolism and Development
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摘要 肝细胞色素P45 0酶技术在药物代谢研究和筛选中的应用是创新药物开发研究的一个重要环节。本文综述了国外就肝P45 0酶应用于药物代谢研究及创新药物开发的现状 ,指出运用肝细胞色素P45 The application of the technique of liver CYP450 enzymes to the study of new drug metabolism and screening is an important link in new drug development. Recent investigations on CYP450 and its application in the study on new drug metabolism and development were reviewed, and it was suggested that liver CYP450 enzymes technique was useful in new drug screening and development in early phase.
出处 《药学进展》 CAS 2000年第6期334-338,共5页 Progress in Pharmaceutical Sciences
关键词 细胞色素P450酶 药物代谢 药物筛选 药物开发 CYP450 Drug metabolism Drug screening
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参考文献1

  • 1W. Kalow. Genetic variation in the human hepatic cytochrome P-450 system[J] 1987,European Journal of Clinical Pharmacology(6):633~641

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