4STEFAN H,FEUERSTEIN T J.Novel anticonvulsant drugs[J].Pharmacol Ther,2007,113(1):165-183.
5NEWPORT D J,PENNELL P B,CALAMARAS M R,et al.Lamotrigine in breast milk and nursing infants:determination of exposure[J].Pediatrics,2008,122(1):e223-231.
6ROWLAND A,ELLIOT D J,WILLIAMS J A,et al.In vitro characterization of lamotrigine N2-glucuronidation and the lamotrigine-valproic acid interaction[J].Drug Metab.Dispos,2006,34(6):1055-1062.
7GLAXO S K.Lamictal(lamotrigine) prescribing information[R].Res Triangle Park,NC,USA,2005.
8YUEN A W,LAND G,WEATHERLEY B C,et al.Sodium valproate acutely inhibits lamotrigine metabolism[J].Br J Clin Pharmacol,1992,33(5):511-513.
9WEINTRAUB D,BUCHSBAUM R,RESOR S R,et al.Eff-ect of antiepileptic drug comedication on lamotrigine clearance[J].Arch Neurol,2005,62(9):1432-1436.
10TOMSON T,LUEF G,SABERS A,et al.Valproate effects on kinetics of lamotrigine in pregnancy and treatment with oral contraceptives[J].Neurology,2006,67(7):1297-1299.
5Anderson D,Martin Y,Barry E.Bidirectional Interaction of Valproate and Lamotrigine in Healthy Subjects[J].Clinical Pharmacology Therapeutics,1996,8:145-156.
6Walker M,Tong X,Perry H.Comparison of Serum,Cerebrospinal Fluid and Brain Extracellar Fluid Pharmacokinetics of Lamotrigine[J].British Journal of Pharmacology,2000,130:242-248.
7Ren S.Determination of Lamotrigine in Biologic Material by a Simple and Rapid Liquid Chromatography Method[ J ].Ther Drug Monit,1998,20(2):209-214.
8Andres M,Marlis F.Adding Valproate to Lamotrige:A Study of Their Pharmacokinetic Interacton[J].Neurology,2000,55:588-591.
9Hainsworth A,Spadoni F,Lavaroni F,et al.Effects of Extracellular pH on the Interaction of Sipatrigine and Lamotrigine with High-Voltage-Activated (HVA) Calcium Channels in Dissocated Neurons of Rat Cortex[J].Neuropharmacology,2001,40(6):784-791.
4DOSIO F, STELLA B, ARPICCO S, et al. Macromolecules as taxane delivery systems [ J ]. Expert Opin Drug Deliv,2011, 8(1) :33-55.
5LIU Y, ZHANG P, FENG N, et al. Optimization and in situ intestinal absorption of self-microemulsifying drug delivery system of oridonin [ J ]. Int J Pharm, 2009,365 ( 1 - 2 ) : 136- 142.
6HOUSAINDOKHT M R, POUR A N. Study the effect of HLB surfactant on particle size distribution of hematite nanoparticles prepared via the reverse microemulsion [ J ]. Solid State Sci,2012,14 ( 5 ) : 622-625.
7ANSARI K A, TORNE S J, VAVIA P R, et al. Paclitaxel loaded nanosponges : in-vitro characterization and cytotoxicity study on MCF-7 cell line culture[ J]. Curr Drug Deliv, 2011,8 (2) : 194-202.
8Norio Y F, Kojiro H, Koji T, et al. Comorbidity of Stevens Johnsonsyndrome and neutropenia associated with lamotrigine: a case report [J].Gen Hosp Psychiatry, 2014, 36(6): 761.e9-761.ell.
9Meldrum B. Action of established and novel anticonvulsant drugs onthe basic mechanisms of epilepsy [J]. Epilepsy Res Suppl,1996,11(7):67-77.
10Stefani A, Spadoni F, Siniscalchi A, et al. Lamotrigine inhibits Ca2+currents in cortical neurons: functional implications [J]. Eur JPharmacol, 2006,307(1): 113-116.
