摘要
目的探讨食管癌并发气管食管瘘病人的治疗方法及其生存期。方法回顾性分析2008年1月至2013年2月期间63例食管癌并发气管食管瘘患者临床资料,根据治疗方法不同分为三组,即金属支架组、鼻饲/胃肠造口组和最佳支持治疗组。对一般性临床资料进行分析和比较,结合治疗后随访情况行生存期分析。结果 63例(50.8%)气管食管瘘患者32例行金属支架置入手术,14例(22.2%)行鼻饲/胃肠造口术,17例(27.0%)行最佳支持治疗。三组在肿瘤分期、瘘口位置、肿瘤初发位置方面比较差异无统计学意义,在年龄及瘘口治疗后化疗方面差异有统计学意义(P<0.05)。三组在瘘口诊断后生存期方面比较差异有统计学意义(P<0.05),即支架组优于鼻饲/胃肠造口组,最佳支持治疗组生存期最短。结论金属支架组能显著延长食管癌恶性气管食管瘘患者生存期,放置金属支架是治疗恶性气管食管瘘的一线治疗方法。
Objective To investigate the therapy and the survival range of esophageal cancer complicated with traeheoesophageal fistula. Methods The clinical data of 63 eases with esophageal cancer complicated with tra- cheoesophageal fistula from 2008 to 2013 were analyzed respectively and divided into three groups according to the methods of treatment, metal stent group, feeding/gastrointestinal colostomy group and support treatment group. The general clinical data were compared and analyzed. Results of the 63 patients, 32 received routine stent implantation surgery （50.8%）, 14 cases （22.2%） received feeding/gastrointestinal colostomy, 17 routine support treatment （27.0~6）. There were no significant differences among three groups in the tumor stages, fistula location, tumor position, but there were significant difference in age and fistula treatment after chemotherapy （P〈0.05）. There were significant difference among the three groups （P〈0.05）. The overall survival range of metal stent group was longest, followed by feeding/ gastrointestinal colostomy group, and support treatment group. Conclusion Metal stent can significantly extend the overall survival range of esophageal malignant tracheoesophageal fistula, and placing metal stents is the first-line ther- apy in the treatment of malignant traeheoesophageal fistula.
出处
《海南医学》
CAS
2013年第24期3624-3626,共3页
Hainan Medical Journal
关键词
食管癌
气管食管瘘
金属支架
生存期
Esophageal cancer
Tracheoesophageal fistula
Metal stent
Overall survival range
