摘要
目的 探讨脑膜外周性原始神经外胚层肿瘤（pPNET）的MRI的特点,以提高对本病的影像表现的认识.方法 回顾性分析9例经病理证实的pPNET患者的影像及病理资料,结合相关文献分析影像及病理特点.结果 9例患者中年龄以10 ～ 20岁者最多,8例与脑膜宽基底相连,并呈梭形.MRI 7例表现为T1WI不均匀等低信号,2例不均匀低信号,9例各病灶内均可见更低信号;T2WI表现为不均匀稍高或高信号,内可见更高信号.增强扫描后肿物呈明显不均匀强化,3例可见短粗脑膜尾征.6例邻近颅骨破坏明显,其中2例突破颅板侵犯头皮下软组织,1例病变推挤右眼导致突出,3例出现远处转移.病理结果示细胞密度大,内有不同程度出血、坏死,细胞胞质透明,免疫组织化学染色检测9例呈CD99和波形蛋白（Vimentin）阳性.结论 脑膜pPNET具有一定的影像学特征,不同于脑膜瘤,有助于该肿瘤的诊断与鉴别诊断.
Objective To analyze the MRI features of Ewing sarcoma/peripheral primitive neuroectodermal tumors（pPNETs） arising from the meninges.Methods The MRI imaging of 9 patients with Ewing sarcoma/pPNET were reviewed retrospectively,and imaging features and pathological characteristics were analyzed.Results The age of most patients ranged from 10 to 20 years.Magnetic resonance revealed a spindle-like lesion with a wide base in 8 cases.The lesions showed heterogenous iso-or hypo-intense signal on T1 WI in 7 cases,heterogenous hypo-iso-intense signal on T1 WI in 2 case,and iso-or mildly hypderisointense on T2WI in all cases.The solid part of the tumor was heterogeneously enhanced after injection of gadolinium with cyst degeneration or necrosis.The ＂dural tail＂ sign could be seen in 3 cases.The adjacent skull erosion could be seen in 6 cases.The breakthrough of the plate of cranium and soft-tissue invasion was present in 2 cases.The right eye proptosis was present in 1 case.The distant metastasis was found in 3 cases.Pathology showed that the lesions had high cell density.Hemorrhage and necrosis could be observed.The cells were like lymphocytes and spindle cells with transparent cytoplasm.CD99 and Vimentin were expressed in all tumor cells.Conclusion The imaging findings of the meningeal pPNET are different from meningiomas,which could be useful for the diagnosis and differential diagnosis.
出处
《中华放射学杂志》
CAS
CSCD
北大核心
2013年第12期1098-1101,共4页
Chinese Journal of Radiology
关键词
脑膜肿瘤
周围神经系统肿瘤
磁共振成像
病理学
Meningeal tumors
Peripheral nervous system neoplasms
Magnetic resonance imaging
Pathology
