摘要
目的比较洛汀新与络活喜对轻中度原发性高血压的疗效。方法分别选取 ３８例与 ３１例原发性高血压（ｅｓｓｅｎｔｉａｌｈｙｐｅｒｔｅｎｓｉｏｎ，以下简称ＥＨ）患者，以洛汀新１０ｍｇ或络活喜５ｍｇ每天晨服一次，治疗４周，比较西药治疗前后的动态血压检测（ａｍｂｕｌａｔｏｒｙｂｌｏｏｄ Ｐｒｅｓｓｕｒｅ ｍｏｎｉｔｏｒｉｎｇ，以下简称 ＡＢＰＭ）结果。结果两药治疗后２４小时平均血压分别由 ＳＢＰ １４３． ７５± １３． ６６， １４７． ６３± １４． ３７（ｍｍＨｇ）降至１２５．１３±１４．８５，１２６．６３±１１．９２（ｍｍＨｇ），ＤＢＰ ９８．８７±９．１４，９４．１３±８．５３（ｍｍＨｇ）降至７６．７５±９．９４，８０．２５±１１．４５（ｍｍＨｇ）；白昼平均血压分别由ＳＢＰ １４７．３８±１０．８６，１５１．６３±１５．３０（ｍｍＨｇ）降至１２７．２５±１２．１０，１３０．６３±１２．８４（ｍｍＨｇ），ＤＢＰ ９０．２５±９．２９，９７．５±８．３７降至７６．２５±１３．６３，８３．１３± ９．４５（ｍｍＨｇ）；夜间平均血压分别由ＳＢＰ１３１．２５±１１．９３，１３３．２５±１２．３７（ｍｍＨｇ）降至１１５．８８±７．３０。
Objective To make a comparison between lotensin and norvasc in the antihypertensive efficacy on mild to moderate essential hypertension. Methods 69 essential hypertension cases were divided at random into lotensin group (38 cases) and norvasc group (31 cases) treated respectively for 4 weeks. Ambulatory blood pressure monitoring was used to assess the antihypertensive efficacy. Results 24 hours after the treatment, the mean blood pressure in 24 hours dripped significantly but no difference was observed between the two drugs in lowing the blood pressure. The side effect of the two drugs were small. Conclusion bath lotensin and norvasc had good efficacy in steadily controlling the blood pressure in mild and moderate EH cases.
出处
《浙江临床医学》
2000年第12期813-814,共2页
Zhejiang Clinical Medical Journal
关键词
原发性高血压
洛汀新
络活喜
动态血压
Essential hypertension
Lotensin
Norvasc
ambulatory
blood pressurte
