摘要
综述CXCL12(SDF-1)/CXCR4轴在肺癌发生、发展过程中调节肺瘤微环境与调控肺瘤进程的作用机制,以及中医药通过调控CXCL12/CXCR4生物轴抑制肿瘤细胞增殖与黏附、抗肿瘤血管生成、抗肿瘤转移作用的研究进展。
This paper reviews the pathologic role of CXCR4/CXCL12 axis in regulating and controlling lung cancer and its mechanism. It presents the research progress on tumor cell proliferation inhibition, tumor cell adhesion, anti-tumor angiogenesis and anti-tumor metastasis by regulating CXCL12 (SDF-1 )/CXCR4 axis with Chinese medicine.
出处
《上海中医药大学学报》
CAS
2013年第6期93-98,共6页
Academic Journal of Shanghai University of Traditional Chinese Medicine
基金
国家自然科学基金资助项目(30973724)