摘要
目的探讨糖化血红蛋白与冠状动脉病变特点的相互关系。方法入选在我院住院的患者1375例,检测糖化血红蛋白,并行冠脉造影术,以Gensini评分评价患者冠状动脉狭窄程度,冠脉病变特点以冠脉病变支数及冠脉狭窄程度来表示。结果糖化血红蛋白与冠脉病变支数显著相关。糖化血红蛋白与Gensini积分呈正相关。在校正了年龄、性别、体重指数、吸烟、饮酒、收缩压、舒张压、肌酐、尿酸、总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、甘油三脂、空腹血糖、高敏C反应蛋白等危险因素后,糖化血红蛋白与Gensin积分的相关性仍存在。结论糖化血红蛋白升高与冠脉狭窄程度加重相关,同时与累及的冠脉支数增加相关。
Objective This study is to investigate the relationship between HbAlc and the characteristics of coronary artery lesions. Methods A total of 1375 patients who were suspected coronary artery disease were enrolled. All these patients underwent coronary artery angiography. HbA 1 c also was inspected. The characteristics of coronary artery lesions were assessed by severity of coronary artery stenosis and the number of coronary vessels with stenosis. Results HbA 1 c significantly correlates with the number of coronary vessels with stenosis. There is a positive correlation between HbAlc and the Gensini score. After adjustment for age, sex, BMI, smoking, drinking, SBP, DBP ,Cr ,UA, CHOL, TG, LDL-C, HDL-C, FBG and HsCRP, HbAlc still correlates with gesini score. Conclusion The increasing of HbAlc correlates with severity of the coronary artery stenosis and the number of coronary vessels with stenosis.
出处
《中国分子心脏病学杂志》
CAS
2013年第6期711-713,共3页
Molecular Cardiology of China
基金
973计划项目(2010CB732601)
院所青年基金支持项目(2013-F10)
