摘要
目的 为观察反应停治疗难治性浆细胞肿瘤的有效性和毒性。方法 共 11例难治性浆细胞肿瘤入选。每晚服用反应停 2 0 0～ 40 0mg。结果 1例因服药未满一月而删除 ,10例中部分缓解 3例 ,进步 3例 ,无效 4例。副作用可以耐受 ,便秘 (7/10 )最常见。结论 30 0～ 40
Objective To investigate the efficacy and toxicity on thalidomide in the treatment of refractory plasma cell neoplasms. Method Oral thalidomide was given to 11 patients at doses of 200-400mg every evening. Results Among the 10 evaluative patients three achieved partial remission (PR) ,3 improved and 4 had no effect. Side effects could been tolerate and the most common one was constipation (7/10). Conclusion Thalidomide at doses of 300-400mg/d for the treatment of refractory plasma cell neoplasms is safe and effective .
出处
《苏州医学院学报》
2000年第11期997-998,1000,共3页
Acta Academiae Medicinae Suzhou
