摘要
目的探讨瑞巴派特联合叶酸和替硝唑治疗慢性萎缩性胃炎临床疗效。方法以120例慢性萎缩性胃炎为研究对象，采用随机数字表法分为两组，观察组使用瑞巴派特片、叶酸联合替硝唑治疗，对照组使用胶体果胶铋胶囊和克拉霉素治疗。经过4周治疗，比较两组患者的临床疗效。结果观察组的总有效率90％，优于对照组的75％（x2=12．347，P〈0．05）。观察组的Hp转阴率为92％，对照组的幽门螺旋杆菌转阴率为72％，观察组优于对照组（X2=8．647，P〈0．05）。结论瑞巴派特、叶酸联合替硝唑有利于治疗慢性萎缩性胃炎，值得临床推广使用。
Objective To explore the clinical efficacy of rebamipide combined with folic acid plus tinidazole in the treatment of patients with chronic atrophic gastritis. Methods 120 patients with chronic atrophic gastritis were randomly divided into two groups. The patients in observation group were given rebamipide, folic acid and tinidazole. The patients in control group were given bismuth pectin and clarithromycin. After treatment for 4 weeks, the clinical efficacy of the two groups was compared. Results The total effective rate of the observation group was 90%, which was significantly higher than 75 % of the control group （ x2 = 12. 347, P 〈 0.05 ）. The negative conversion rate of heli- cobacter pylori in observation group was 92% ,which was significantly higher than 72% in the control group （ x2 = 8. 647,P 〈 0.05 ）. Conclusion Rebamipide, folic acid combined with tinidazole is beneficial for the treatment of patients with chronic atrophic gastritis. It is worthy of clinical application.
出处
《中国基层医药》
CAS
2013年第24期3728-3729,共2页
Chinese Journal of Primary Medicine and Pharmacy
关键词
胃炎
萎缩性
幽门螺杆菌
叶酸
替硝唑
果胶类
铋
瑞巴派特
Gastritis, atrophic
Helicobacter pylori
Folic acid
Tinidazole
Pectins
Bismuth
Rebamipide
