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钆贝葡胺与钆喷酸葡胺对单发脑转移瘤患者MRI T1WI增强扫描诊断价值的对比 被引量:2

Comparison of diagnostic value of Gd-BOPTA in and Gd-DTPA MRI T1WI contrast enhanced for single brain metastases
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摘要 目的比较钆贝葡胺与钆喷酸葡胺在脑内单发转移瘤增强扫描中的价值。方法选择81例单发脑转移瘤患者,首先行钆喷酸葡胺增强扫描,剂量0.1 mmol/kg;2 d后行钆贝葡胺增强扫描,剂量0.1 mmol/kg。结果①钆贝葡胺强化后,病变形态、病变边缘、强化程度及增强范围均显著优于钆喷酸葡胺,差异具有统计学意义(z=12.3232,14.43534,11.4536,12.4232,P<0.05);②增强扫描后,钆贝葡胺强化图像对比信噪比均显著高于钆喷酸葡胺,强化病灶/正常脑组织增强比均显著高于钆喷酸葡胺,差异具有统计学意义(t=12.3456,12.3465,11.2675,3.7865,3.8796,3.8781,P<0.05)。结论钆贝葡胺增强扫描对单发脑转移瘤病变形态、病变边缘、强化程度及增强范围显示更优,其图像对比信噪比及病灶/正常脑组织增强比更高。 Objective To compare the Gd-BOPTA and Gd-DTPA contrast enhanced diagnostic value of single brain metastases. Methods A total of 81 cases of single brain metastases patients were chosen, first used Gd-DTPA en- hanced scan,the dose was 0.1 mmol/kg. 2 d after it, they underwent Gd-BOPTA enhanced scan,the dose was 0.1 mmol/kg. Results (1)After Gd-BOPTA enhancement the lesion morphology,lesion edges, and the degree of enhance- ment were significantly enhanced range than Gd-DTPA(Z=12.3232,14.43534,11.4536,12.4232,P 〈 0.05). @)while the enhanced scan, Gd-BOPTA enhanced image contrast shellfish were significantly higher signal to noise ratio of Gd-I)TPA,enhanced lesions shellfish/enhancement of normal brain tissue were significantly higher than that of Gd- DTPA (t= 12.3456,12.3465,11.2675, 3.7865,3.8796,3.8781 ,P 〈 0.05). Conclusion Gd-BOPTA enhanced MRI for shellfish single brain metastases lesion morphology, lesion edges, the degree of enhancement and enhanced range dis- vlav better, its sitmal to noise ratio and image contrast lesions are higher than normal brain tissue enhancement.
作者 朱峰 沈君
出处 《中国现代医生》 2013年第34期106-108,共3页 China Modern Doctor
基金 国家自然科学基金(30870691)
关键词 钆贝葡胺 钆喷酸葡胺 磁共振 转移瘤 单发 Gd-BOPTA Gd-DTPA Magnetic resonance Metastases Single
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