摘要
目的分析中西医结合法用于支气管哮喘急性发作治疗中的效果与安全性。方法对Cochrance、OVID、Pubmed图书馆数据库进行计算机检索,查找单纯西医治疗与中西医治疗支气管哮喘急性发作的随机对照研究。筛选出的研究数据RevMan 5.1软件进行Meta分析,了解中西医结合疗法效果与安全性。结果共纳入4个研究(n=688)的支气管哮喘急性发作患者,Meta统计显示,相比单纯西医治疗,中西医结合治疗可有效改善急性发作时呼气峰流速(MD=10.65[2.81,18.49],P=0.008),糖皮质激素用量更少(RR=0.75[0.62,0.92],NNT=6.58[3.55,45.87],P=0.005),在缩短住院时间(RR=0.78[0.57,1.06],NNT=19[9,+∞],P=0.110)、不良反应(RR=0.85[0.67,1.09],NNT=17[9,+∞],P=0.314)方面差异不具统计学意义。结论采用中西医结合疗法可有效改善临床症状与患者肺功能,不良反应与单纯西医治疗相近,证实此种疗法安全有效。
Objective To analyze the effect of traditional Chinese medicine and Western medicine for the treatment of acute attack of bronchial asthma. Methods Using computer retrieval of database Cochrance, OVID, Pubmed library, data analysis of Meta. Results A total of 4 studies were included（n=688）, compared with the pure western medicine treatment, treatment can effectively improve the acute attack of peak expiratory flow of integrated traditional Chinese and Western Medicine（MD=10.65[2.81, 18.49], P=0.008）, symptom improvement effect is stronger（RR=0.75[O.62, 0.92], NNT=7[4, 46], P=0.005）, the hospitalization time（RR=0.78[0.57, 1.06], NNT=19[9, ＋∞],P=0.110）, adverse reaction（RR=0.85[0.67, 1.09], NNT=17[9, ＋∞],P=0.314）. The difference was not statistically significant. Conclusion Combined therapy of traditional Chinese medicine and Western medicine is effective and safe in use.
出处
《中国医药指南》
2013年第32期326-327,共2页
Guide of China Medicine
关键词
中西医结合
支气管哮喘急性发作
疗效
安全性
Combine traditional Chinese and Western medicine
Acute attack of bronchial asthma
Efficacy
Safety
