摘要
A型肉毒毒素(BTX-A)治疗多种以不自主或异常肌肉收缩为特征表现的运动障碍性疾病是近年神经科治疗领域的重要进展之一。本文综述肉毒毒素治疗应用的原理、适应证、远隔效应、免疫反应等问题,充分肯定其临床应用的发展前景。对其局限性也阐述了看法和建议。
Botulinum toxin type A,a powerful presynaptically active neuromuscu-lar blocking agent, represents a major breakthrough in the treatment of focal dystonia and other neurological disorders characterized by involuntary or abnormal muscle contractions. The article reviews the mechanism, indications, methods, remote effects and im-munoreaction of direct intramuscular injection of botulinum toxin.
