摘要
目的 :研究晚期妊娠补充高剂量鱼油对母体前列环素 ( PGI2 )和血栓素 A2 ( TXA2 )的影响及安全性。方法 :将 58名晚期妊娠妇女分成两组 :鱼油组和对照组 ;在鱼油补充前后相应期用放免法测定母血 PGI2 和 TXA2 代谢产物。结果 :补充后鱼油组母血 TXA2 代谢产物 ( TXB2 )显著降低 ,对母血 PGI2代谢产物 ( 6-K-PGF1 a)无统计意义影响 ,造成血 TXB2 / 6-K-PGF1 a比值下降 ;母亲和新生儿未见出血倾向并发症。结论 :补充鱼油制剂对孕妇廿烷类代谢的影响 。
Objective:We studied the effect ofhigh dose supplement of fish oil in the late pregnancy on maternal prostacyclin(PGI 2 ),thromboxane(TXA 2 )and its security.Methods:58 women in the late pregnancy were randomly assigned to two group received fish oil or no fish oil supplement.Metabolites of PGI 2 and TXA 2 were measured with radioimmunoassay before and after supplement of fish oil.Results:Fish oil supplement in late pregnancy can decrease maternal serum TXA 2 significantly.It has no effect on PGI 2 ,thus decrease TXB 2 /6 k PGF 1 a,Com plication that cause maternal and perinatal bleeding tendency in the supplement of fish oil were not found.Conclusion:The results suggest that high dose supplement of fish oil in the late pregnancy can prevent pregnancy induce hypertension.
出处
《锦州医学院学报》
2000年第5期19-22,共4页
Journal of Jinzhou Medical College
