摘要
目的 探讨SRT治疗颅内肿瘤的方法、效果及适应症。方法 总结79例颅内肿瘤SRT治疗及随访资料。结果 79例颅内肿瘤分别采用BRW 分次、GTC 低分次、多分次、高分次治疗。平均随访13.39月,1年生存率72.34％,生存期19.57月;实际肿瘤控制率87.5％。结论 SRT疗效确切,优于单次治疗,且并发症低于后者。SRT 治疗需要严格掌握适应症,并根据病变部位、体积、性质、一般情况及放疗病史等选择治疗方式和剂量。
Objective To study the effects,indication and methods of stereotactic radiotherapy (SRT) forintracranial tumors. Methods The treatment and follow - up data of 79 cases of intracranial tumors treated bySRT, were summarized. The indication and methods were discussed. Results Patients were treated byfractionated BRW therapy, low - fractionated GTC therapy, multi - fractionated GTC therapy and hyper -fractionated GTC therapy,respectively. In 79 cases, 103 lesions were treated with 204 targets in 956 fractions.No immediate adverse reaction occurred. Patients were followed up 1 month to 3.67 years (mean 13. 38months). The one - year survival was 72.34%, and the survival time was 19.57 months. The actual local tumorcontrol was 87.5%. For patients in the same condition, all curative parameters of SRT were superior to those ofsingle high - dose X - knife,and the edema incidence of SRT was much lower (P<0.05). Conclusion Thefindings suggested definite curative effects of SRT on intracranial tumors. The curative effects of SRT weresuperior to those of single high - dose stereotactic radiosurgery, and the complications of SRT were much less.Yet the indication of SRT should be limited strictly .The methods and dose of SRT should he selected properly,according to the location,nature and volume of the tumor, the general condition and radiotherapy history of thepatient.
关键词
颅内肿瘤
立体定向放射治疗
X刀治疗
病例分析
Intracranial tumor
Stereotactic radiotherapy
X-Knife Stereotactic radiosurgery
