摘要
目的探讨宫颈细胞学电脑自动辅助阅片(TIS)在大样本筛查中的有效性。方法选取2012年3月至2012年8月期间5486例宫颈液基细胞学检查及其中174例宫颈细胞学异常者行阴道镜下病理组织学活检。结果经TIS和传统人工阅片两种阅片方法比较,TIS阅片诊断低度鳞状上皮内病变(LISL)以上病变阳性率为1.53%,经传统人工阅片为1.00%,检出率增加53%,差异有统计学意义(χ2=6.12,P<0.05);对174例TIS检出阳性病例行组织病理学活检,其中38例高度鳞状上皮内病变(HSIL)以上病变的组织学活检阳性率为97.37%。结论与人工阅片相比,电脑辅助阅片系统使宫颈病变的细胞学阳性检出率显著增加,并对HSIL以上病变拥有较高的阳性预测值。
Objective To investigate the effectiveness of cytology thinprep imaging system （TIS） in large sample screening. Methods From February 2012 to August 2012, 5486 samples of liguid based cytology were choosen, and 174 samples with cy- tological abnormality were given histopathological biopsy under colposcope. Results The positive predictive value for LSIL and above pathological changes by TIS was 1.53% , and the positive predictive value for LSIL and above pathological changes by manual thinprep review （MR） was 1.00%. The detectable value increased by 53% , and there was significant difference（ X2 = 6. 2,P 〈 0. 05 ）. Among the 174 samples of histopathological biopsy for patients who showed positive value by TIS, the positive predictive value for 38 samples with HSIL and above pathological chaneges was 97.37%. Conclusion Compared with manual thinprep review, TIS markedly increases the cytological detectable rate of pathological changes of cervix and has higher positive predictive value for HSIL and above pathological changes.
出处
《临床医学》
CAS
2013年第10期34-35,共2页
Clinical Medicine
关键词
电脑辅助阅片
宫颈细胞学筛查
人工阅片
Thinprep imaging system
Cervical cytology screening
Manual thinprep review
