摘要
目的:探讨盆腔孤立性纤维性肿瘤(solitary fibrous tumor,SFT)的诊断及治疗方法。方法:回顾性分析2008年4月至2012年2月间手术治疗的9例盆腔SFT患者的临床资料。结果:男性7例,女性2例,中位年龄56岁,经体检发现者6例,有症状者3例,CT检查显示肿瘤内部不均匀软组织密度,增强扫描呈不均匀强化,无特异性表现。9例患者均行肿瘤切除术,其中5例行脏器联合切除。组织病理检查见瘤细胞呈梭形、短梭形及圆形,核分裂相少见。免疫组织化学检查显示CD34、CD99、Bcl-2、Vimentin阳性率为100%,对诊断有明确意义。患者的中位随访期为34个月,1例术后34个月死亡,余8例无复发。结论:盆腔SFT的确诊需要组织病理及免疫组织化学检查,手术完整切除是治疗的主要方法,多需联合脏器切除,多数患者的预后良好。
To explore the clinical diagnosis and surgical treatment of pelvic solitary fibrous tumor （SFT）. Methods： The data of nine cases of pelvic solitary fibrous tumor from April 2008 to February 2012 were reviewed retrospectively. Results： There were 7 male and 2 female patients in this group with a median age of 56 years, of whom 6 were asymptomatic. Their CT showed the tissue density was inhomogencous. Multivisceral resections were performed in 5 patients. Microscopically, the tumor cells were shuttle-shaped, short spindle-shaped or round, and mitoses was rare, immunohistochemistry： CD34, CD99, Bcl-2, Vimentin positive rates were 100%. One patient died 34 months after the surgery, and there was no recurrence in other patients. Conclusion： Pelvic SFT is rare. It is difficult to make an accurate diagnosis. Surgery is the most effective therapy. Multivisceral resections are needed sometimes. The prognosis is good for most patients.
出处
《北京大学学报（医学版）》
CAS
CSCD
北大核心
2013年第6期960-964,共5页
Journal of Peking University:Health Sciences
关键词
孤立性纤维瘤
盆腔肿瘤
诊断
外科手术
预后
Solitary fibrous tumors, Pelvic neoplasms, Diagnosis, Surgical procedures, operative, Prognosis
