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E-Cadherin与干细胞的调控研究进展

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摘要 干细胞是一类分化程度低,具有分化成不同类型细胞潜能且可自我更新的一类细胞。粘附分子是指由细胞产生、存在于细胞表面、介导细胞与细胞间或细胞与基质间相互接触和结合的一类分子。粘附分子可以使干细胞锚定于niche中,为干细胞-niche信号传递搭建平台,同时提供了极性线索引导干细胞分裂,对干细胞的对称和不对称分裂的选择及其连续、长期的自我更新起重要作用。
出处 《中国矫形外科杂志》 CAS CSCD 北大核心 2013年第24期2503-2505,共3页 Orthopedic Journal of China
基金 国家自然科学基金(编号:81271990)
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