摘要
背景:毫米波在中国临床应用已有近20年经验,但其具体机制以及临床疗效仍缺乏循证医学依据。目的:通过对国内外近10余年来毫米波在临床各类病症的应用及其机制研究进行综述。方法:应用计算机检索1998年1月至2012年12月CNKI、中国标准全文数据库和Science Direct数据库,在标题和摘要中以"毫米波;生物学机制;实验研究;临床应用"或"millimeter wave,biological mechanisms,experimental studies,clinical application"为检索词进行检索。纳入与毫米波的生物效应密切相关文献,最终选择64篇文章进行分析。结果与结论:①毫米波疗法用于人体时,虽其穿透组织的深度仅达表皮,但其能量与人体内的一些大分子发生谐振而产生治疗作用。②毫米波疗法对含水组织有较好的亲和力,可改善局部组织的新陈代谢和血液循环,加速病理产物和代谢产物吸收的排泄,从而达到消炎、消肿、止痛等治疗目的。③毫米波疗法具有广泛的生物学效应,在临床上可用于多种疾病的单纯物理治疗之一或辅助治疗。④其具体应用参数理论基础、生物效应及分子细胞学机制仍不很明确,还需在其适应证上进行多学科、大样本的临床验证。
BACKGROUND: Millimeter wave has been applied in clinic for about 20 years, while the mechanisms and clinical curative effect are still undefined and lacked of evidence based medicine. OBJECTIVE: To review the clinical application and mechanism of millimeter wave in various diseases in the past 10 years. METHODS: A computer-based online search was performed in the CNKI database, China Standard database and Science Direct database from January1998 to December 2012 with the key words of "millimeter wave, biological mechanisms, experimental studies, clinical application" put in the title and abstract. The articles related to the biological effect of millimeter wave were included, and finally, 68 articles were included for review. RESULTS AND CONCLUSION: When the millimeter wave used in the human body, it can only go through the skin, but its energy can resonance with some molecules in the tissues and provide the treatment effects. Millimeter wave therapy has a good affinity for aqueous tissue, which can improve the metabolism and blood circulation of partial tissues, and can enhance the metabolic and pathological product absorption and excretory, thus can eliminate inflammatory, alleviate swell and relieve pain. Millimeter wave filed has comprehensive
出处
《中国组织工程研究》
CAS
CSCD
2013年第46期8102-8107,共6页
Chinese Journal of Tissue Engineering Research
基金
国家自然科学基金(81273774)~~