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异丙酚联合氯胺酮麻醉对PCNL患者炎症介质TNF-α的影响 被引量：4

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摘要 目的探讨异丙酚联合氯胺酮麻醉对经皮肾镜碎石术(PCNL)患者炎症介质肿瘤坏死因了-α(TNF-α)的影响。方法择期拟行经皮肾镜取石术的全麻患者60例,分为C组(对照)和PK组(异丙酚联合氯胺酮),每组30例。两组患者分别在麻醉诱导前(T1)、麻醉诱导后(T2)、手术开始后60min(T3)及手术结束时(T4)采静脉血,测定血清TNF-α水平。结果与C组相比,PK组在T1、T2时刻血清TNF-α的浓度无明显差异(P>0.05),而T3、T4时血清TNF-α的浓度均明显低于C组(P<0.05)。结论异丙酚联合氯胺酮麻醉,能有效降低PCNL手术患者TNF-α的释放,抑制炎性反应。
作者 唐万英 柯齐斌 余相地 朱贤林
机构地区 三峡大学第一临床医学院麻醉科
出处 《重庆医学》 CAS CSCD 北大核心 2013年第34期4187-4189,共3页 Chongqing medicine
关键词 异丙酚 氯胺酮 内窥镜检查 尿路碎石 肿瘤坏死因子Α
分类号 R614 [医药卫生—麻醉学]
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参考文献11

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二级参考文献41

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共引文献13

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重庆医学
2013年 第34期

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