摘要
以天然多糖做碳化原料，经磺化后得到碳负载固体酸。以其为催化剂，由芳香醛、β-酮酸酯和尿素缩合制备了系列3，4-二氢嘧啶-2-酮衍生物。以乙醇为溶剂回流反应2．5～5h，产物产率在72％-89％之间。产物结构经’HNMR，IR确证。
A series of 3,4-dihydrepyrimidin-2 （1 H）-ones were prepared through the Biginelli condensation reactions of aromatic aldehydes, keto ester and urea catalyzed by carbon-based solid acid, which was synthesized after pyrolysis of natural polysaccharide and subsequently functionalised with sulfonated groups. The reactions were carried out under reflux in ethanol for 2. 5-5 h. The yields of the products had between 72% - 89%. All the products had been characterized by 1H NMR and IR spectra.
出处
《化学研究与应用》
CAS
CSCD
北大核心
2013年第12期1697-1701,共5页
Chemical Research and Application
基金
河北省自然科学基金项目(B2011204051)资助
河北农业大学理工基金项目(LG201107)资助
