摘要
目的探讨住院患者中合并急性肾损伤(AKI)的病因及影响AKI患者死亡的危险因素。方法回顾性分析广东医学院附属南山医院2009年1月至2012年5月615例住院患者发生AKI的临床资料,分析其病因分型、肾衰类型,应用Logistic回归对影响AKI患者死亡的危险因素进行分析。结果 615例合并急性肾损伤的住院患者中,肾前性因素占60%,肾性因素占24%,肾后性因素占6%,多种原因并存占10%。创伤、感染、脑血管意外、合并慢性肾脏病是AKI的主要病因。肿瘤、急性左心衰、创伤、脑血管意外、多器官功能障碍综合征、呼吸衰竭、感染等是影响AKI患者死亡的重要危险因素(P均<0.05)。结论住院患者发生AKI病因较多,应重视住院患者发生AKI的病因和影响其死亡的危险因素,及早给予防治,改善合并AKI患者预后,提高其生存率。
Objective To assess the etiological factors and mortality risk factors for hospitalized patients complicated with a- cute kidney injury （AKI）. Methods A retrospective study of 61.5 hospitalized patients with AKI in the Affiliated Nanshan Hospital of Guangdong Medical College from January 2009 to May 2012 was conducted. Clinical data were collected to analyze their etiological factors and renal failure categories.. Binary multivariate logistic regression analysis was applied to investigate the mortality risk factors. Results Prerenal,renal and post-renal factors contributed to 60% ,24% and 6% ,respectively, of the 615 AKI patients. Multiple factors were blamed in 10% of the patients. Trauma,infection, cerebral vascular accident and combined chronic kidney disease were the major risk factors of AKI. Tumor （P 〈 0. 05 ） , acute left heart failure （ P 〈 0. 05 ） , trauma （ P 〈 0. 05 ） , eerebrovaseular accident （ P 〈 0.05 ） , multiple organ dysfunction syndrome （ MODS ） （ P 〈 0. 05 ）, respiratory failure （ P 〈 0. 05 ）, and infection （ P 〈 0. 05 ） were important mortality risks factors. Conclusion Diverse factors may contribute to AKI in hospitalized patients, and attention should be paid to the etiology of AKI and the risk factors of mortality. Early prevention and treatment may improve the prognosis and survival of the AKI patients.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2013年第12期957-960,共4页
Chinese Journal of Practical Internal Medicine
基金
广东省医学科研基金(2011A570)
关键词
急性肾损伤
住院患者
感染
慢性肾脏病
心力衰竭
acute kidney injury
hospitalized patients
infection
chronic kidney disease
heart failure
