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一氧化氮和一氧化氮合酶与肾脏的关系研究 被引量：1

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摘要 1980年，Furehgott等Ⅲ首先发现了血管内皮细胞可合成和释放血管内皮舒张因子（endothelium—derivedrelaxingfactor．EDRF）。1987年，Palmer等[21证明EDRF即为一氧化氮（nitricoxide。NO）。随着科学技术的发展，NO在机体生理、病理过程中所发挥的重要作用不断被发现，如今，NO已经成为生物医学研究的热点和前沿之一。一氧化氮合酶（nitricoxidesynthase，NOS）是NO合成的催化酶。本文主要就NO和NOS的肾内作用研究进展作一综述。
作者 原慧 高原
机构地区 合肥医学院珠海校区
出处 《现代医药卫生》 2013年第23期3580-3582,共3页 Journal of Modern Medicine & Health
关键词 一氧化氮 一氧化氮合酶 肾 血管内皮 综述
分类号 R743.31 [医药卫生—神经病学与精神病学]
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参考文献24

  • 1Furchgott RF, Zawadzki JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine[J]. Nature, 1980,288(5789) : 373-376.
  • 2Palmer RM, Ferrige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor[J]. Nature, 1987,327 (6122) : 524-526.
  • 3Chen K,Popel AS. Theoretical analysis of biochemical pathways of nitric oxide release from vascular endothelial cells[J]. Free Ra- dic Biol Med, 2006,41 (4) : 668-680.
  • 4王转锁,李凤良,宋钦华.一氧化氮与糖尿病肾病的研究[J].医学综述,2004,10(9):560-562. 被引量：7
  • 5Mitchell JA, Ali F, Bailey L, et al. Role of nitric oxide and pros- tacyclin as vasoactive hormones released by the endothelium[J]. Exp Physiol, 2008,93( 1 ) : 141-147.
  • 6Kim YM, Choi BM, Kim YS, et al. Protective effect of p53 in vas- cular smooth muscle cells against nitric oxide-induced apoptosis is mediated by up-regulation of heme oxygenase-2[J]. BMB Rep, 2008,41 (2) : 164-169.
  • 7De Ridder M, Van Esch G, Engels B, et al. Hypoxic tumor cell radiosensitization:role of the iNOS/NO pathway[J]. Bull Cancer, 2008,95 (3) : 282-291.
  • 8Dias-Junior CA, Cau SB, Tanus-Santos JE. Role of nitric oxide in the control of the pulmonary circulation:physiological, pathophy- siological, and therapeutic implications[J]. J Bras Pneumol, 2008, 34(6) :412-419.
  • 9Levy RM, Prince JM, Billiar TR. Nitric oxide : a clinical primer[J]. Crit Care Med, 2005,33 ( 12 Suppl) : S492-495.
  • 10Garcia X,Stein F. Nitric oxide[J]. Semin Pediatr Infect Dis,2006, 17(2) :55-57.

二级参考文献48

  • 1Strijbos PJLM, Leach MJ, Garthwaite J. Vicious cycle involving Na+ channels, Glutamate release, and NMDA receptors mediates Delayed Neurodegeneration through Nitric oxide formation[J].J Neurosci, 1996,16(16) :5004-5013.
  • 2Ladecola C. Bright and dark sides of nitric oxide in ischemic brain injuty[J]. Trends Neurosci, 1997,20(3) : 132-139.
  • 3King AJ, Brenner BM. Endothelium-derived vasoactive factors and the renal vasculature[ J]. Am J Physiol, 1991,260(4 Pt 2) : R653-662.
  • 4Kone BC. Nitric oxide in renal health and disease[J]. Am J Kidney Dis, 1997,30(3) :311-333.
  • 5Nathan C. Nitric oxide as a secretory product of mammalian cells[J].FASEB J, 1992,6(12) :3051-3064.
  • 6Moncada S, Higgs A. The L-arginine-nitric oxide pathway[ J ], N Engl J Med, 1993,329(27) :2002-2012.
  • 7Craven PA, DeRubertis FR, Melhem M. Nitric oxide in diabetic nephropathy[ J]. Kidney Int Suppl, 1997,60[ Suppl ] : S46-53,.
  • 8Bank N,Aynedjian HS. Role of EDRF (nitric oxide) in diabetic renal hwoerfiltration [ J ]. Kidney Int, 1993,43 (6) : 1306-1312.
  • 9Tolins JP, Shuhz PJ, Raij L, et al, Abnormal renal hemodynamic response to reduced renal perfusion pressure in diabetic rats: role of NO[ J ]. Am J Physiol, 1993,265 (6 Pt 2) : F886-895.
  • 10Wu G. Nitric oxide synthesis and the effect of aminoguanidine and NGmonomethyl-L-arginine on the onset of diabetes in the spontaneously diabetic BB rat[J]. Diabetes, 1995,44(3) :360-364.

共引文献11

同被引文献35

  • 1Zhang L, Wang F, Wang L,et a/. Prevalence of chronic kidney dis- ease in China: a cross-sectional survey [ J]. Lancet, 2012,379 (9818) :815-822.
  • 2Brenner BM ,Meyer TW, Hostetter TH. Dietary protein intake and the progressive nature of kidney disease : the role of hemodynami- cally mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease[J]. N Engl J Med,1982,307(ll) :652-659.
  • 3Fine LG, Orphanides C, Norman JT, Progressive renal disease:the chronic hypoxia hypothesis [ J ]. Kidney Int Suppl, 1998, 65: s74-78.
  • 4Evans RG, Ince C, Joles JA, et al. Haemodynamic influences on kidney oxygenation: clinical implications of integrative physio- logy [ J ]. Clin Exp Pharmacol Physiol,2013,40 (2) : 106-122.
  • 5Haase VH. Mechanisms of hypoxia responses in renal tissue [ J ]. J Am Soc Nephrol,2013,24(4) :537-541.
  • 6Regner KR, Roman RJ. Role of medullary blood flow in the patho- genesis of renal ischemia-repeffusion injury [ J]. Curt Opin Neph- rol Hypertens ,2012,21 ( 1 ) :33-38.
  • 7Nangaku M, Rosenherger C, Heyman SN, et al. Regulation of hypoxia-inducible factor in kidney disease [ J ]. Clin Exp Pharma- col Physiol,2013,40(2) :148-157.
  • 8Semenza GL,Wang GL. A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation [ J ]. Mol Cell Bio1,1992,12(12) :5447-5454.
  • 9Tanaka T, Nangaku M. The role of hypoxia, increased oxygen con- sumption, and hypoxia-inducible faetor-I alpha in progression of chronic kidney disease E J ]. Curt Opin Nephrol Hypertens, 2010, 19( 1 ) :43-50.
  • 10Basile DP, Donohoe D, Roethe K, et al. Renal ischemie injury results in permanent damage to pefitubular capillaries and influ- ences long-term function [ J ]. Am J Physiol Renal Physiol, 2001, 281 (5) :F887-899.

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现代医药卫生
2013年 第23期

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