摘要
目的 :探讨热性惊厥 (FC)时异常脑电图 (EEG)与以后癫的发作 ,与FC的再发及预防性治疗的关系。方法 :记录 186例 4 6岁患儿FC后EEG。结果 :首次EEG异常率为 33 % ;EEG异常率与Ⅰ级亲属的热惊厥史无关系 ;EEG异常率与FC临床特征 (局灶性发作和FC持续时间 >15分钟 )有关 ;首次FC的EEG异常率为 12 % ,随着FC再发次数的增多逐渐增高 ,FC再发 3次以上的患儿中 ,其EEG异常率高达 35 8%～ 5 3 3% ;3岁以内FC儿其EEG异常率不明显 ,3岁以后的FC儿EEG的异常率则逐渐增多 ,有统计意义 ;部分患儿多次EEG检查出现发作性棘波 ,其中 3例随访 4～ 8年 ,最后诊断为癫。结论 :EEG异常率与Ⅰ级亲属是否有FC史无关 ,与FC临床特征有关系 ;FC再发与EEG异常、年龄有明显关系 ;EEG多次异常FC可发展为癫 ;建议预防性治疗。
Objective:To study the relationship between abnormal electroencephalogram (EEG)of febrile convulsion (FC)children and their further seizures,relapse as well as preventive treatment.Method:The EEG in 186 FC children at the age of 4-6 years was recorded.Result:In first time of FC children, abnormality rate of EEG was 33%;There was no relationship between abnormality rate of EEG and the FC history of their I grade relatives,but it was related to clinical feature of FC (local seizures and FC lasting>15 min);The first time abnormality rate of EEG was12%,and it increased with FC repeat times increasing,in>3 times FC,the abnormality rate of EEG could be 35 8%～53 3%;The abnormal EEG was not significant negative in FC children less than 3 years but become significant after 3 years old,some children(3 of them)become to be epileptic patients 4-8 years later.Conclusion:There might be no relationship between abnormality rate of EEG and FC history of their I grade relatives, abnormality rate of EEG might be related to clinical feature of FC; further seizures might be related to abnormal EEG and ages;several times of abnormal EEG can lead to epilepsy.
关键词
热性惊厥
脑电图
再发
癫痫
Febrile convulsion
Electroencephalogram
Further seizures
Epilepsy
