摘要
目的:研究单纯性肥胖患儿BMI相关危险因素,为预防肥胖相关疾病在儿童中的流行提供一定的指导。方法:对68例单纯性肥胖儿童测量身高、体重,留空腹血并检测血脂、肝功、血糖、胰岛素、C反应蛋白、单核细胞趋化因子、内脂素。结果:线性相关分析显示,BMI与C反应蛋白、单核细胞趋化因子、谷草转氨酶、甘油三酯、总胆固醇、高密度脂蛋白、低密度脂蛋白、胰岛素等具有简单线性相关;多元线性回归显示,甘油三酯、胰岛素、C反应蛋白、低密度脂蛋白与BMI密切相关。结论:甘油三酯、胰岛素、C反应蛋白、低密度脂蛋白与肥胖相关疾病密切相关,肥胖儿童通过降低其BMI水平,对于预防血脂紊乱、炎症性疾病及2型糖尿病的发生有重要意义。
Objective：To study the relation between BMI and risk factors of obesity-related disease and provide some guidance for preventing of obesity-related disease prevalence in children .Method：We recruited 68 obese children and the subjects’ body weight ,height were measured according to standardized techniques .Also lip-ids ,liver function ,blood glucose ,insulin ,C-reactive protein ,monocyte chemotactic factor ,visfatin were tested . Results ：The linear correlation analysis showed that BMI had a simple linear correlation with C-reactive protein , monocyte chemotactic factor ,aspartate aminotransferase ,triglycerides ,total cholesterol ,high density lipoprotein , LDL and insulin ,we analysis with multivariate linear regression and it showed that triglycerides ,insulin ,C-reactive protein ,low-density lipoprotein were closely related with BMI .Conclusion ：Triglycerides ,insulin ,C-reactive pro-tein and low-density lipoprotein are closely related to obesity-related diseases .It is important for obese children re-duce the level of BMI to prevent lipid disorders ,inflammatory diseases and type 2 diabetes .
出处
《陕西医学杂志》
CAS
2013年第11期1462-1464,共3页
Shaanxi Medical Journal
基金
国家自然科学基金项目(81172689)
