摘要
目的:观察右美托咪啶(DEX)辅助颈丛神经阻滞对甲状腺手术的麻醉效果及术后恶心呕吐(PONV)发生率。方法:择期甲状腺手术患者80例,ASAI^II级,随机均分为两组:DEX组(D组)和咪唑安定组(M组)。记录麻醉前(T0)、麻醉后10min(T1)、切皮即刻(T2)、切皮后5min(T3)、处理甲状腺上极时(T4)及手术结束时(T5)的MAP、HR、SpO2、OOA/S评分及麻醉效果,术后记录患者的PONV发生率。结果:T2、T3、T4时D组HR、MAP低于M组。D组OAA/S评分4~5分者为3人,1~3分者为37人,优于M组。D组麻醉效果优良例数为34,麻醉效果差为6,好于M组。PONV发生率D组为11例,低于N组21例(P均<0.05)。结论:右美托咪定用于颈丛阻滞下甲状腺手术,镇静镇痛效果佳,可减小颈丛阻滞及手术导致的心血管副作用,且降低PONV发生率。
Objective：To investigate the preventive effect of Dexmedetomidine against postoperative nausea and vomiting（PONV） after Thyroidectomy. Methods：80 ASAⅠor Ⅱ thyroidectomy patients were randomized to receive midazolam（Group M）, Dexmedetomidine （Group D）, with 40 patients in every group. The changes of MAP,HR,SpO2,OOA/S scale were monitored and recored before cervical plexus（T0）, 10minutes later（T1）,and at incision（T2）, 5 minutes later（T3）, at separation of thyroid upper extreme（T4）and at suture（T5）. PONV and safety assessments were performed continuously during the first 24h after anesthesia. Results：The values of MAP,HR were significant higher in group M at T2,T3,T4. On time points of T3,T4 and T5, the OOA/S scales in group M were higher than those in group D（P〈0.05）. The incidence of PONV was significantly lower in group D than that in group M within 24h postoperatively （P〈0.05）. Conclusions：Dexmedetomidine as a supplement to cervical plexus block for thyroidectomy can effectively provide desirable blunting of blood pressure and heart rate, and significantly decrease the incidence of PONV.
出处
《中国医药导刊》
2013年第11期1850-1851,共2页
Chinese Journal of Medicinal Guide
关键词
右美托咪定
颈丛阻滞
血流动力学
PONV
Dexmedetomidine
Cervical plexus block
Thyroidextomy
PONV
