摘要
目的探讨肾移植与血液透析患者的生存质量及其影响因素.方法选择2011年3月至2012年7月在昆明医科大学第一附属医院和云南省肾脏病医院维持性血液透析或肾移植3个月以上的患者142例,所有患者均检测生化指标,并采用KDQOL-SFTM1.2量表进行问卷调查.结果 (1)肾移植组在SF-36总分及其生理、心理领域得分均高于血液透析组,差异有统计学意义(P<0.05);(2)肾移植组在KDTA总分及其分支领域除认知功能、社会交往的质量和睡眠以外的分值也均高于血液透析组,差异有统计学意义(P<0.05);(3)相关性分析表明:2组患者SF-36总分以及KDTA总分均与血清白蛋白呈正相关,与年龄呈负相关,2组患者的SF-36总分与血红蛋白和受教育程度呈正相关.结论肾移植患者的总体生存质量优于血液透析患者.
Objective Investigate the quality of life （QoL） and its related factors of end stage renal disease （ESRD） patients subjected to kidney transplantation or hemodialysis. Methods From March 2011 to July 2012, patients subjected to kidney transplantation or hemodialysis more than three months hospitalized in the first affiliated hospital of Kunming Medical University and the Yunnan Kidney Disease Hospital were enrolled. Their biochemical indexes were determined and questionnaire survey was performed using KDQOL-SFTM1.2 scale to assess the QoL of ESRD patients. Results （1） The QoL of renal transplantation group was significantly higher than hemodialysis group in the 36-item health survey （SF-36）,its physiological and psychological field scores,and the difference was statistically significant （ 〈0.001）;（2） The QoL of renal transplantation group was significantly higher than hemodialysis group in the kidney disease-targeted scales （KDTA） and its fields excepting cognitive function （CF）, quality of social interaction （QSI） and sleep field, and the difference was statistically significant （ 〈0.001）; （3） Correlation analysis showed that the scores of SF-36 and KDTA in two groups were positively associated with albumin （Alb） but negatively associated with age. The scores of SF-36 in two groups were positively associated with hemoglobin （Hb） and degree of education. Conclusion The results showed that the QoL of kidney transplantation patients was much higher than that of hemodialysis patients.
出处
《昆明医科大学学报》
CAS
2013年第11期46-49,共4页
Journal of Kunming Medical University
基金
云南省科技计划联合专项项目(2010CD164)
云南省教育厅科学研究基金资助项目(2010Z032)
关键词
肾移植
血液透析
生存质量
Kidney transplantation
Hemodialysis
Quality of life
