福建省畲族人群单根据TSH水平来评定甲状腺功能异常患病率的调查被引量：3

The prevalence of thyroid dysfunction according to TSH level alone in She ethnic minority group of Fujian province

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摘要于2009年采用分层抽样的方法对福建省宁德市5523名畲族人群进行流行病学调查，最终5080名研究对象进入研究。该人群中甲状腺功能异常的患病率为12．1％，TSH低于正常范围者有124名（2．4％），高于正常范围者有491名（9．7％）。甲状腺过氧化物酶抗体（TPOAb）阳性率为10．8％（男性7．4％及女性13．5％，P〈0．01），TSH异常的人群中TPOAb阳性率较TSH正常者高。研究结果显示，TSH与TPOAb关系密切．在甲状腺功能亢讲及甲状腺功能减退人群中．自身免疫可能均起着萤要的作用。 In 2009, 5 523 participants of She nationality living in Ningde City of Fujian province were multistage-stratified and randomly collected, and 5 080 were enrolled in analysis eventually. The TSH screening （reference range, 0.3-3.0 mIU/L） revealed biochemical hyperthyroidism in 2.4% （2. 1% of males and 2.7% of females） and biochemical hypothyroidism in 9.7 % （7.4% of males and 11.4% of females） of the participants. The prevalence of positive TPOAbs was 10.8% （7.4% of males and 13.5 % of females）. TSH values outside the normal reference range were associated with a higher prevalence of positive TPOAbs, indicating that autoimmunity seems to be an important factor in both hyperthyroidism and hypothyroidism.

作者吴娟林奉森乔玉芳朱香清陈兆樵林丽香陈刚

机构地区福建医科大学省立临床医学院宁德市医院内分泌科福建省立医院内分泌科

出处《中华内分泌代谢杂志》 CAS CSCD 北大核心 2013年第11期968-970,共3页 Chinese Journal of Endocrinology and Metabolism

关键词畲族甲状腺疾病 TSH 甲状腺过氧化物酶抗体 She ethnicity Thyroid dysfunction TSH TPOAb

分类号 R581 [医药卫生—内分泌]

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