摘要
目的评价血浆置换治疗重症肝炎患者的临床效果。方法分别于治疗前、后检测患者凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、纤维蛋白原(FIB)、凝血酶时间(TT)、D-二聚体诸项指标,探讨这些指标在血浆置换前后的变化。结果早、中期组与晚期组比较在血浆置换前后凝血指标均有统计学差异(P<0.05);早期组同中期组比较差别无统计学意义(P>0.05);早、中期组本组内比较血浆置换前后凝血指标的差异有统计学意义(P<0.05),晚期组血浆置换前后比较,凝血指标无统计学差异(P>0.05)。结论血浆置换治疗是治疗早、中期肝衰竭的有效手段,可以有效改善凝血指标,降低D-二聚体水平。
Objective To explore the clinical value of plasma exchange in hepatic failure. Methods A total of 115 patients with live failure underwent plasma exchange. Their prothrombin time （ PT）, thromboplastin time （ TT）, activated partial thromboplastin time （APTT）, fibrin （FIB） and D-dimer （D-D） were detected before and after treatment. The changes were studied. Results After treatment, there were significant differences in the above parameters between early-term group or mid-term group and late-term group （P 〈 0, 05）. There was no significant difference between the early-term group and the mid-term group （ P 〉 0.05 ）. In the early-term group and the mid-term group, there were significant differences between before and after treatment （ P 〈 0.05 ）. In lateterm group, there was no significant difference between before and after treatment （ P 〉 0.05 ）. Conclusion Plasma exchange treatment is an effective treatment method to early-and mid-term hepatic failure for it helps to improve blood coagulation indexes and lower levels of D-D.
出处
《临床军医杂志》
CAS
2013年第11期1115-1116,共2页
Clinical Journal of Medical Officers
关键词
血浆置换
肝衰竭
凝血指标
D-二聚体.
plasma exchange
hepatic failure
blood coagulation indicator
D-dimer
