摘要
目的 探讨大肠癌淋巴结转移相关的病理学因素。方法 对 3 68例大肠癌切除标本按统一标准 ,进行组织学分类、浸润深度、癌周淋巴细胞反应等项检查 ,探讨其与淋巴结内癌转移的关系。结果 淋巴结内癌转移率为 3 3 4% ,其中肠旁组淋巴结转移率占 77 2 % ,肠系膜淋巴结及系膜动脉结扎处淋巴结转移率占 17 9%和 4 9%。癌肿长径 >6cm及浸润深度达浆膜外 ,癌周淋巴细胞反应强度 >+++时癌转移率最高 (P <0 0 0 5 ) ,组织学分级级别越高 ,癌转移率越高。组织类型与癌转移率有明显相关性 (P <0 0 5 ) ;结论 大肠癌淋巴结内癌转移以肠旁组为主 ,常为逐站转移 ,转移率与肿瘤大小、浸润深度呈正相关 ,与分化程度及淋巴细胞反应强度呈负相关 ,与组织学类型有明显相关性。
Objective To study the pathologic factors of the lymph node mestastasis of colorectal carcinoma.Methods 368 redical resection samples from the patients with colorectal carcinoma were observed with the same standard,Including the histological classification,infiltration depth,lymphocyte reaction round the cancer and the approach to the relation between the lymph node metastasis and the situation.Results The total rate of lymph node metastasis is 33.4%,inclading 77.2% the rate of lynph node metastasis beside the colorectum,17.9% and 4.9% the respective rates of mesentery and mesenteric artery ligate point.When the diameter of cancer is over 6 cm,the infiltratiing depth reaches the outside of the serous coat and the intensity of lymphocyte reaction beside cancer is over +++,the rate of cancer metastasis is the highest ( P <0 005) The higher the grade of histology,the higher the rate of metastasis of carcinoma.The rate of carcinoma metastasis has also a correlation with the histological classification( P <0 005) Conclusions Lymph node metastasis from colorectal carcinoma is beside coloretum first,the rate of it has a positive relation with the diameter of cancer and infiltration depth a negative relation with grade of differentiation of carcinoma and reaction of lymphocyte and an obvious relation with histological classification.
出处
《河南肿瘤学杂志》
2000年第6期403-404,共2页
Henan Journal of Oncology
关键词
大肠癌
淋巴结
转移
病理
colorectal carcinoma
lymph node
metastasis
pathology
