摘要
目的:研究妊娠高血压综合征与血清超敏C反应蛋白、脐动脉血流动力学变化的相关性。方法:选取妊娠高血压患者110例,其中妊娠期高血压组60例,子痫前期组50例,设置健康对照组50例,测量血清超敏C反应蛋白及脐动脉血流动力学参数。结果:妊娠高血压组血清超敏C反应蛋白水平明显高于正常组(P﹤0.01),脐动脉血流S/D比值、RI值均比对照组增高(P﹤0.01),随着病情加重血清超敏C反应蛋白,脐动脉血流S/D比值、RI值增高更显著,观察组1和观察组2比较有统计学差异(P﹤0.01)。结论:妊娠高血压综合征与血清超敏C反应蛋白、胎儿脐动脉血流改变有一定的相关性,通过血清C反应蛋白值和脐动脉血流参数可了解妊娠高血压的程度,预测胎儿宫内生长环境,预测妊高征的预后。
Objective： To research the correlation between hypertensive disorder complicating pregnancy （HDCP） and serum hy- persensitive C -reactive protein （CRP） , hemodynamic change of umbilical artery. Methods： A total of 110 patients with HDCP were se- lected, including 60 patients in gestational hypertension group and 50 patients in preeelampsia group ; 50 normotensive women were selected as control group ; the levels of serum hypersensitive CRP and hemodynamic parameters of umbilical artery in the three groups were measured. Results： The serum level of hypersensitive CRP in gestational hypertension group was statistically significantly higher than that in control group （P 〈 0. 01 ） ; umbilical artery S/D ratio and resistance index （RI） in umbilical artery in gestational hypertension group was statistical- ly significantly higher than that in control group （ P 〈 0. 01 ） ; serum hypersensitive CRP levels, S/D ratios and RI values in umbilical artery increased significantly with aggravation of the disease, there were statistically significant differences between gestational hypertension group and preeelampsia group （P 〈 0.01 ） . Conclusion： There is a certain correlation between HDCP and serum hypersensitive CRP, hemody- namie change of umbilical artery; detecting serum hypersensitive CRP level and hemodynamie parameters can predict the degree of HDCP, intrauterine growth environment of fetuses, and prognosis of patients with HDCP.
出处
《中国妇幼保健》
CAS
北大核心
2013年第34期5614-5616,共3页
Maternal and Child Health Care of China
关键词
妊娠高血压综合征
超敏C反应蛋白
脐动脉
Hypertensive disorder complicating pregnancy
Hypersensitive C -reactive protein
Umbilical artery
