摘要
目的探讨糖皮质激素辅治儿童支原体感染性大叶性肺炎的临床疗效。方法对2011年8月至2012年8月确诊的60例肺炎支原体感染性大叶性肺炎患儿的临床资料进行回顾性分析。根据激素使用情况分为激素组与非激素组。激素组37例，予以口服强的松1mg/（kg·d），连用1～2周；非激素组23例。对其热程、住院天数及病灶吸收情况等进行比较分析。结果60例肺炎支原体感染性大叶性肺炎患儿均采集双份血清（间隔2周），MP-IgM均为阳性，滴度最高可达1：1280；胸部x线片及胸部CT表现为双侧或单侧大叶肺实变；合并胸腔积液15例。激素组热程明显缩短，临床症状很快得到改善，胸部x线片或CT示肺部病变很快好转。结论肺炎支原体感染性大叶性肺炎患儿除应用大环内酯类抗生索外，可合理应用激素。使用糖皮质激素治疗可以缩短热程，促进病灶早日吸收。
Objective To study the effectiveness of low doses of glucocorticoid in the assistance treatment of mycoplasma pneumoniae lobar pneumonia in children. Methods 60 cases of myeoplasma pneumoniae lobar pneumonia in children diagnosed in August 2011 to August 2012 were retrospectively analyzed. All cases were divided into hormone using group and non-hormone using group according to the usage of hormone.Hormone using group of 37 cases, oral prednisone[1 mg/（kg/d）] 1-2 weeks; The non-hormone using group of 23 cases. The thermal process, hospitalization days and lesions absorption comparatively analyse. Results 60 cases of mycoplasma pneumoniae lobar pneumonia in children are collected double serum （spacing 2 weeks） from MP- lgM 4 times drop degree rise, drop degrees up to 1 ： 1280; Chest X-ray and chest CT manifestations in bilateral or unilateral lobe lung consolidation; Merger of 15 cases of pleural effusion. The thermal process of hormone group is significantly shortened, clinical symptoms improved quickly, chest X-ray or CT lung disease better soon. Conclusion Except applies Macrolides antibiotic, hormone can reasonable application in Mycoplasma pneumoniae lobar pneumonia in children. Using glucocorticoid therapy can shorten the heat process, promote lesions absorption at an early date.
出处
《中国医药指南》
2013年第31期44-45,共2页
Guide of China Medicine
关键词
糖皮质激素
大叶性肺炎
肺炎支原体
儿童
Glucocorticoid
Lobar pneumonia
Mycoplasma pneumoniae
Children
