摘要
目的：采用64-MDCT评价冠心病患者升主动脉弹性与高血压的相关性。方法：对135例拟诊冠心病的受检者行回顾性心电门控技术冠状动脉CTA和冠状动脉造影（CAG）检查。测量受试者血压，重组升主动脉0％～95％R-R间期间隔5％的图像，采用MATLAB软件自动描绘并测量各R—R间期主动脉横截面积，然后计算出升主动脉弹性值。将受试者分为非高血压组（n=54）和高血压组（n=81）。结果：高血压组升主动脉弹性低于非高血压组（t=7．81，P〈0．001）。多元线性回归表明高血压是升主动脉弹性值的独立影响因子（B=-0．835，t=7．18，P〈0．001）。结论：升主动脉弹性与高血压有较好的相关性，升主动脉弹性的及时、准确评价有助于心血管疾病的早期预警。
Objective： To assess the relationship between ascending thoracic aorta distensibility and hypertension in coronary artery disease （CAD） patients by 64-multidetector computed tomography. Method： In all, 135 patients with suspected CAD were enrolled in this study and underwent retrospective ECG-gated coronary CTA and CAG. Every patient＇s blood pressure was measured before and after the coronary CTA respectively. The ascending aortal images of 20 phases between 0% and 95% of the R-R intervals with an increment of 5% was reformatted and the aortal area of the images was measured by MATLAB software, and then we can calculate the aortic distensibility. The patients can be divided into hypertension subjects （n = 81） and normal subjects （n = 54）. Result： The aortic distensibility of the Patients was remarkably lower in hypertension subjects than that in normal subjects（t- 7.81% P〈 0.001）. Multivariate linear regression demonstrated that hypertension was the independent risk thctors of aortic distensibility （B -0.835, t = 7.18, P 〈 0.001）. Conclusion： The ascending thoracic aorta distensibility had a significant relationship with hypertension. The estimate of aortic distensibility may play an important role in the prediction of cardiovascular disease.
出处
《CT理论与应用研究（中英文）》
2013年第4期685-691,共7页
Computerized Tomography Theory and Applications
关键词
冠心病
主动脉弹性
高血压
MDCT
coronary artery disease （CAD）
aortic distensibility
hypertension
MDCT
