摘要
目的 :探讨癌抗原 12 5 (CA12 5 )检测在腹膜透析中的临床意义。方法 :采用 EL ISA方法 ,检测 5 0例连续性不卧床腹膜透析 (CAPD)患者在非感染期与感染期及其治疗前后的透出液 CA12 5水平的变化。 结果 :随着腹膜透析时间的延长 ,非感染期患者透出液 CA12 5水平逐渐下降 ,两者呈负相关 (r=- 0 .6 7,P<0 .0 1)。感染期患者透出液 CA12 5水平明显增高达(6 3.12± 11.72 ) U/ ml,治疗后明显下降为 (39.2 0± 6 .97) U/ ml,差异有显著性 (P<0 .0 1)。结论 :动态观察 CA12 5在 CAPD患者透出液中的变化 ,可作为评价腹膜功能、判断预后的参考指标之一。
Objective: To investigate the clinical significance of detecting cancer antigen (CA125) in peritoneal dialysis patients. Methods: CA125 levels in peritoneal effluent were assessed by ELISA. Results: With the duration of peritoneal dialysis prolonged, the levels of CA125 in peritoneal effluent among CAPD patients decreased. CA125 levels of peritonitis increased obviously in experimental group(63.12±11.72)U/ml compared with control group, then decreased after treatment (39.20± 6.97)U/ml . Conclusion: The regular changes of the levels of CA125 may be used as one of signs for estimating peritoneal function and judging prognosis. [
出处
《第二军医大学学报》
CAS
CSCD
北大核心
2000年第11期1038-1040,共3页
Academic Journal of Second Military Medical University
基金
国家自然科学基金资助项目 ( 3 92 70 3 4 5 )
