摘要
目的:探讨外科重症监护病房病原菌及其耐药性的变化特点。方法:回顾总结1996年1月~1999年12月采集所有病人病原菌标本,及其对临床常用抗生素的药敏结果进行分析。结果:革兰阴性菌和真菌比例上升;对大肠埃希菌、产ESBL菌和不动杆菌属明显上升。革兰阴性菌对泰能、头孢他定、丁胺卡那、环丙沙星较敏感;革兰阳性菌对万古霉素仍有很高的敏感性。结论:为了减少细菌耐药和真菌感染,应合理选用抗生素。
Objective: To investigate the change of variety in pathogen strains and their resistance to antimicro bial agents in surgical intensive care unit(ICU). Methods: The change in pathogen strains of all patients from Jan. 1996 to Dec. 1999 were analyzed retrospectively and their susceptibility to antimicrobial agents were studied. Results: The incidence of Gram-negative bacterial and fungal infection was on the rise; the incidence of E. coli, ESBL's(Extended Spectrum 6-Lactamases) and Acinetobacter increased significantly. Gram-negative bacteria were senstive to Imipenem, Ceftazidime, Amikacin and Ciprofloxacin and Gram-positive bacteria were still sensitive to Vancomycin. Conclusions: In order to decrease the incidence of antibiotic resistance and fungal infection, the appropriate choice of antimicrobial agents is proposed.
出处
《外科理论与实践》
2000年第4期257-259,共3页
Journal of Surgery Concepts & Practice
关键词
外科重症监护病房
病原菌
耐药性
抗生素
intensive care unit Pathogen strains Resistance to antimicrobial agents